1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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CAS No:
70641-51-9
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Formula:
C27H58NO6P
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Chemical Name:
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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Synonyms:
4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-Trioxa-4-phosphaheptacosan-1-aminium 4-oxide;NSC 324368;NSC 343649;Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine;Ro 14-5243;ET-18-OCH?;ET-18-OCH3;EDELFOSINE
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CAS No:
Description
1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic Attributes
523.73
523.400146
343649|324368
DTXSID9045766
white
Drug Information
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases. (See all compounds classified as Phosphodiesterase Inhibitors.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
1-O-octadecyl-2-methyl-3-phosphatidylcholine
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Use and Manufacturing
Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.
Computed Properties
Molecular Weight:523.7
XLogP3:7.6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:27
Exact Mass:523.40017557
Monoisotopic Mass:523.40017557
Topological Polar Surface Area:77
Heavy Atom Count:35
Complexity:492
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
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