Kebuzone
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Kebuzone
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CAS No:
853-34-9
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Formula:
C19H18N2O3
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Chemical Name:
Kebuzone
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Synonyms:
3,5-Pyrazolidinedione,4-(3-oxobutyl)-1,2-diphenyl-;4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione;Ketazon;Ketophenylbutazone;1,2-Diphenyl-4-(2-acetylethyl)pyrazolidine-3,5-dione;γ-Oxophenylbutazone;Kebuzone;γ-Ketazone;γ-Ketophenylbutazone;Ketazone;Chebutan;Chepirol;Chetazol;Chetil;Chetopir;Recheton;Reuchetal;Ejor;Gammachetone;Ketanol;Ketason;Chetazolidin;Phloguron;Copirene;Pecnon;KPB
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CAS No:
Description
ChEBI: A pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group.
Kebuzone is a pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group. It has a role as a non-steroidal anti-inflammatory drug and a non-narcotic analgesic. It is a member of pyrazolidines and a methyl ketone. It derives from a phenylbutazone.|Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
Kebuzone Basic Attributes
322.358
322.36
212-715-7
4VD83UL6Y6
DTXSID00234500
M - Musculo-skeletal system
2933990090
Characteristics
57.69000
1.25
1.2±0.1 g/cm3
126.0-128.5 °C
462.8±37.0 °C at 760 mmHg
199.5±18.9 °C
1.599
174.2mg/L(20 ºC)
LD50 oral in rat: 720mg/kg
Safety Information
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
4-(3-oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione