 Home > Encyclopedia > Pyromellitic acid

Pyromellitic acid

Pyromellitic acid structure

CAS No:
89-05-4
Formula:
C10H6O8
Chemical Name:
Pyromellitic acid
Synonyms:
USAF xr-20;1,2,4,5-BenzenetetracarboxyL;benzene-1,2,4,5-tetracarboxylate;1,2,4,5-Benzenetetracarboxylic acid,Pyromellitic acid;1,2,4,5-Benzenetetracarboxylic acid, 96% 100GR;1,2,4,5-Benzenetetracarboxylic acid, 96% 5GR;1,2,4,5-BENZENETETRACARBOXYLIC ACID FOR;Pyrome1htic Acid
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

White powder. Absorbs moisture slowly if exposed to atmosphere. Soluble in alcohol, slightly soluble in water.

Pyromellitic acid is a tetracarboxylic acid that is benzene substituted by four carboxy groups at positions 1, 2, 4 and 5 respectively. It is a member of benzoic acids and a tetracarboxylic acid.

Dissolve it in 5.7 parts of hot dimethylformamide, decolorise, filter and cool. The precipitate is collected and dried in air. The solvent is removed by heating in an oven at 150-170o for several hours. It also crystallises from water. [Beilstein 9 H 997, 9 IV 3804.]

Pyromellitic acid Basic Attributes

Molecular Weight：

254.15

Exact Mass：

254.15

EC Number：

201-879-5

UNII：

D9UXG2U6ZU

NSC Number：

6369

TSCA：

TSCA listed

DSSTox ID：

DTXSID8044466

Color/Form：

White to very slightly yellow

HScode：

29173980

Characteristics

PSA：

149.20000

XLogP3：

0.44

Appearance：

White to very slightly yellow Crystalline Powder

Density：

0,56 g/cm3

Melting Point：

281-284.5 °C(lit.)

Boiling Point：

317.36°C (rough estimate)

Flash Point：

325 °C

Refractive Index：

1.7010 (estimate)

Water Solubility：

1.5 g/100 mL (20 ºC)

Storage Conditions：

Store below +30°C.

PKA：

pK1: 1.92;pK2: 2.87;pK3: 4.49;pK4: 5.63 (25°C)

Henrys Law Constant：

1.6×1013mol/(m3Pa) at 25℃, Yaws (2003)

Dissociation Constants：

1.87 (at 25 °C)

Critical Temperature & Pressure：

Store below +30°C.

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

26-36-37/39-24/25

RTECS Number：

DB9275000

Marks：

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, strong bases.

Precautionary statement(s)：

P280-P305 + P351 + P338-P337 + P313

Hazard Statements：

Skin irritant, may be carcinogenic.

GHS Classification：

|Warning|H315 (45.54%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 125 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

pyromellitic acid

Pyromellitic acid Use and Manufacturing

Methods of Manufacturing

It is obtained by oxidation of 1, 2, 4, 5-tetratoluene (or 5-isopropyl-1, 2, 4-trimethylbenzene), or by chloromethylation and oxidation of xylene.

Uses

1,2,4,5-benzenetetracarboxylic acid is used for the synthesis of the polyimide, pyromellitic octyl, etc., it is the main raw material of matting curing agent.

Intermediates

Pyromellitic acid (PMA) is mainly used as intermediate for powder coating. Product Data Sheet

Manufacturing Info：

All other basic organic chemical manufacturing|1,2,4,5-Benzenetetracarboxylic acid: ACTIVE

Computed Properties

Molecular Weight:254.15
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:254.00626715
Monoisotopic Mass:254.00626715
Topological Polar Surface Area:149
Heavy Atom Count:18
Complexity:327
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Pyromellitic acid

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Most Professional factory Supply High Quality Pyromellitic Acid CAS 89-05-4

CAS No.: 89-05-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

1,2,4,5-Benzenetetracarboxylic acid

CAS No.: 89-05-4

Content: 99.00%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high quality1,2,4,5-Benzenetetracarboxylic acid 99% see COA Kanbei

CAS No.: 89-05-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

Factory supply 1,2,4,5-Benzenetetracarboxylic acid CAS NO.89-05-4

CAS No.: 89-05-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Honour Enterprise Company Limited Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of Semaglutide,Tirzepatide,API,Enzyme

15 Years Factory Supply CAS 89-05-4 Pyromellitic acid

CAS No.: 89-05-4

Grade: Industrial Grade

Content: 99.0%

Inquiry