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Home > Encyclopedia > 3,5-Dihydroxy-2-naphthalenecarboxylic acid

3,5-Dihydroxy-2-naphthalenecarboxylic acid

3,5-Dihydroxy-2-naphthalenecarboxylic acid structure

3,5-Dihydroxy-2-naphthalenecarboxylic acid 

structure
  • CAS No:

    89-35-0

  • Formula:

    C11H8O4

  • Chemical Name:

    3,5-Dihydroxy-2-naphthalenecarboxylic acid

  • Synonyms:

    2-Naphthalenecarboxylic acid,3,5-dihydroxy-;2-Naphthoic acid,3,5-dihydroxy-;3,5-Dihydroxy-2-naphthalenecarboxylic acid;1,7-Dihydroxy-6-naphthoic acid;2,8-Dihydroxy-3-naphthoic acid;3,5-Dihydroxy-2-carboxynaphthalene;3,5-Dihydroxy-2-naphthoic acid;2,8-Dihydroxynaphthalene-3-carboxylic acid;NSC 50694;1,7-Dihydroxy-6-naphthalenecarboxylic acid

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

3,5-Dihydroxy-2-naphthalenecarboxylic acid Basic Attributes

204.179

204.18

201-900-8

50694

DTXSID00237470

2918290000

Characteristics

77.76000

2.52

1.5±0.1 g/cm3

275-280 °C(lit.)

442.2±35.0 °C at 760 mmHg

235.3±22.4 °C

1.762

Safety Information

NONH for all modes of transport

3

R36/37/38

S26-S36

Xi: Irritant;

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

3,5-Dihydroxy-2-naphthalenecarboxylic acid Use and Manufacturing

3,5-Dihydroxy-2-naphthoic Acid is used as a negative or positive NMDA receptor inhibitor, via allosteric control. NMDA receptors regulate CHN (central nervous system) functions.It is also used as a protein tyrosine phosphatase inhibitor due to the benzofuran-like moiety in the substructure.

Computed Properties

Molecular Weight:204.18
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.04225873
Monoisotopic Mass:204.04225873
Topological Polar Surface Area:77.8
Heavy Atom Count:15
Complexity:253
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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