Sennoside A
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Sennoside A
structure -
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CAS No:
81-27-6
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Formula:
C42H38O20
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Chemical Name:
Sennoside A
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Synonyms:
[9,9′-Bianthracene]-2,2′-dicarboxylic acid,5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-,(9R,9′R)-;Sennoside A;[9,9′-Bianthracene]-2,2′-dicarboxylic acid,5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-,(R*,R*)-;rel-(9R,9′R)-5,5′-Bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid;Glysennid;Gentle Nature;NSC 112929;26926-11-4;28680-34-4
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CAS No:
Description
Sennoside A is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia)[1]. Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication[2].
Characteristics
348
1.2
Senna (powdered) is a yellow-brown powder with a slight odor and taste. (NTP, 1992)
1.7±0.1 g/cm3
220 - 243 °C
1144.8°C at 760 mmHg
348.6±27.8 °C
1.763
less than 1 mg/mL at 66° F (NTP, 1992)
D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane)
Safety Information
NONH for all modes of transport
3
22
22-45
P261, P264, P270, P272, P280, P285, P301+P312, P302+P352, P304+P341, P321, P330, P333+P313, P342+P311, P363, P501
H302
Sennoside A Use and Manufacturing
a natural anthroquinonone glucoside calcium complex with laxative properties
Drug Function and Efficacy
Laxative effect by stimulating colonic motility and inhibiting water and electrolyte reabsorption in the intestine
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