2-METHOXY-5-NITRO-6-PICOLINE
-
2-METHOXY-5-NITRO-6-PICOLINE
structure -
-
CAS No:
5467-69-6
-
Formula:
C7H8N2O3
-
Chemical Name:
2-METHOXY-5-NITRO-6-PICOLINE
-
Synonyms:
2-甲氧基-5-硝基-6-甲基吡啶(订作1个月);2-Methoxy-5-nitropyridine;6-Methoxy-3-nitro-picoline;6-METHOXY-3-NITRO-2-ICOLINE;6-METHOXY-3-NITRO-2-PICOLINE;2-METHOXY-5-NITRO-6-PICOLINE;2-methyl-3-nitro-6-methoxypyridine;2-METHOXY-5-NITRO-6-METHYLPYRIDINE;6-Methoxy-3-nitro-2-methylpyridine;6-methoxy-2-methyl-3-nitropyridine
- Categories:
-
CAS No:
2-METHOXY-5-NITRO-6-PICOLINE Use and Manufacturing
To intermediate 73 (1.95 g, 0.015 mol) at r. t. , was added HNO3 60percent (7ml). The mixture became reddish brown with generation of heat and NO2. CONC. H2SO4 (7ML) was then added. The solution was stirred at 80°C overnight. Into the cooled reaction mixture was poured ice water (70ml) and the solution was neutralized with CACO3. The aqueous solution was extracted with EtOAc (3X50 mL) and the combined organic extracts were dried over anh. NA2SO4. The solids were filtered and the solvent was evaporated to dryness to give the title compound (2.25 g, 86percent) as a yellow solid. NMR ('H, DMSO): 8 8.3 (d, 1H) ; 6.8 (d, 1H) ; 4 (s, 3H), 2.7 (s, 3H).Sodium metal (0.119g, 5.1mmol) was dissolved in methanol (6ml) at 0°C (ice bath), 6-chloro-2-methyl-3-nitro-pyridine (0.30g, 1.7mmol) was added and the mixture was stirred at 0°C until the complete consumption of 6-chloro-2-methyl-3-nitro-pyridine (4h). Acetic acid (0.306g, 5.1mmol) was added and the solution was concentrated under reduced pressure. The residue was dissolved in ethyl acetate (20 ml), washed with water (10 ml), dried over anhydrous Na6-methoxy-3-nitro-2-picoline 6-methoxy-3-nitro-2-picoline
Computed Properties
Molecular Weight:168.15
XLogP3:1.4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:168.05349212
Monoisotopic Mass:168.05349212
Topological Polar Surface Area:67.9
Heavy Atom Count:12
Complexity:169
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-METHOXY-5-NITRO-6-PICOLINE
-
![China]()
CN
2 YRS
Business licensedTrader Supplier of Pharmaceutical intermediatesInquiryUnit Price: $1 /KG EXWCAS No.: 5467-69-6Grade: Industrial GradeContent: 99% -
![China]()
CN
1 YR
Business licensed Certified factoryManufactory Supplier of SR17018
Latest News on 2-METHOXY-5-NITRO-6-PICOLINE
- Evonik Reportedly Rejects BASF’s €10.3 Billion Takeover Bid as Too Low
- Evonik to Cut 3,200 Jobs Globally as Restructuring Deepens Across German Operations
- BASF Raises Acid Chloride and Chloroformate Capacity by 30% at Ludwigshafen
- U.S. Formally Publishes India PFA Trade Cases, Raising New Barriers for Fluoropolymer Supply
- Ashland Explores Sale as Private Equity Circles $4.5 Billion Specialty Chemicals Portfolio
Learn More Other Chemicals
-
Cholesteryl oleyl carbonate
17110-51-9
-
2-broMo-5-iodobenzoic acid Methyl ester
717880-58-5
-
(S)-(+)-Tetrahydrofurfurylamine
7175-81-7
-
Ethyl 4-fluoro-3-nitrobenzoate Formula
367-80-6
-
4-[2,2-dichloro-1-(4-methoxyphenyl)ethenyl]-2-methoxy-1-phenylmethoxybenzene Formula
90047-68-0
-
Dioxopromethazine hydrochloride Formula
15374-15-9
-
Phosphorodiamidic acid, tetraethyl-, 2-propenyl ester Structure
75219-49-7
-
Benzene, 4-[4'-(3-butenyl)[1,1'-bicyclohexyl]-4-yl]-1,2-difluoro-, [trans(trans)]- Structure
155266-68-5
-
What is 1-BENZYLPIPERIDINE-4-CARBONITRILE
62718-31-4
-
What is Cinchoninic acid, 6-amino-2-methyl- (6CI)
103858-07-7