Bile, extract
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Bile, extract
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CAS No:
8008-63-7
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Chemical Name:
Bile, extract
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Synonyms:
Bile,extract;69430-22-4
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CAS No:
Safety Information
NONH for all modes of transport
3
P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, P501
H302
|Warning|H302 (28.57%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 13 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Bile, extract Use and Manufacturing
Bile, extract: ACTIVE|Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)-: ACTIVE
Computed Properties
Molecular Weight:408.6
XLogP3:3.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:408.28757437
Monoisotopic Mass:408.28757437
Topological Polar Surface Area:98
Heavy Atom Count:29
Complexity:637
Undefined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It mainly has anti-inflammatory and analgesic effects. 1. Anti-inflammatory: Houzheng Pills can inhibit the formation of tissue inflammation. Oral administration of 89 mg/kg has a significant inhibitory effect on the inflammation caused by xylene-coated mouse ears, but has no significant inhibitory effect on the swelling of the foot joints caused by egg white. 2. Analgesia: Oral administration of 89 mg/kg Houzheng Pills has a significant analgesic effect on thermal stimulation of mice, but the same dose has no significant effect on peripheral pain caused by glacial acetic acid.
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