(7α,14R)-14-(Acetyloxy)-7-hydroxykaur-16-ene-3,15-dione
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(7α,14R)-14-(Acetyloxy)-7-hydroxykaur-16-ene-3,15-dione
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CAS No:
80508-81-2
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Formula:
C22H30O5
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Chemical Name:
(7α,14R)-14-(Acetyloxy)-7-hydroxykaur-16-ene-3,15-dione
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Synonyms:
Kaur-16-ene-3,15-dione,14-(acetyloxy)-7-hydroxy-,(7α,14R)-;(7α,14R)-14-(Acetyloxy)-7-hydroxykaur-16-ene-3,15-dione;Glaucocalyxin B;Wangzaozin C;14β-Acetoxy-7α-hydroxy-ent-kaur-16-ene-3,15-dione
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CAS No:
Description
Glaucocalyxin B is an ent kaurane diterpenoid isolated from the Chinese traditional medicine Rabdosia japonica with anticancer and antitumor activity; decreases the growth of HL-60 cells with an IC50 of approximately 5.86 μM at 24 h.
Characteristics
80.67000
1.37
1.2±0.1 g/cm3
190.5-191 °C
509.1±50.0 °C at 760 mmHg
172.9±23.6 °C
1.554
Computed Properties
Molecular Weight:374.5
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:374.20932405
Monoisotopic Mass:374.20932405
Topological Polar Surface Area:80.7
Heavy Atom Count:27
Complexity:752
Defined Atom Stereocenter Count:5
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
(7α,14R)-14-(Acetyloxy)-7-hydroxykaur-16-ene-3,15-dione
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