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Dihydrostreptomycin sulfate

Dihydrostreptomycin sulfate structure

CAS No:
5490-27-7
Formula:
C21H41N7O12.³/2H2O4S
Chemical Name:
Dihydrostreptomycin sulfate
Synonyms:
D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-,sulfate (2:3);Streptomycin,dihydro-,sulfate (2:3) (salt);D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-,sulfate (2:3) (salt);Dihydrostreptomycin 3/2 sulfate;Dihydrostreptomycin sulfate;Didromycine;Dihydrostreptomycin sesquisulfate;Panstreptin;Didromycin;Streptomagna;Double-mycin;Sol-Mycin;28779-37-5
Categories:
Biochemical Engineering > Saccharides

Description

Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep.

Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bactericidal properties. Dihydrostreptomycin sulfate inhibits protein synthesis by binding to the 30S ribosomal subunit. This antibiotic is active against most gram-positive and gram-negative organisms and is used in the treatment of tuberculosis and tulemia.|A semi-synthetic aminoglycoside antibiotic that is used in the treatment of TUBERCULOSIS.

Dihydrostreptomycin sulfate Basic Attributes

Molecular Weight：

1451.38

Exact Mass：

1460.464779

EC Number：

226-823-7

UNII：

T7D4876IUE

DSSTox ID：

DTXSID6045824

NCI Thesaurus Code：

C47492

HScode：

2941200000

Characteristics

PSA：

927.35000

XLogP3：

-9.21650

Appearance：

white to light yellow crystalline

Boiling Point：

954.5ºC at 760 mmHg

Flash Point：

531.1ºC

Water Solubility：

soluble in waterH2O: 50 mg/mL, clear, faintly yellow

Storage Conditions：

2-8°C

Specific rotation：

D25 -88.5° (1% soln)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

24/25

RTECS Number：

WK2236000

Marks：

Hazard Statements：

H302

GHS Classification：

|Danger|H302 (68.84%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P314, P322, P330, P363, P405, and P501|Aggregated GHS information provided by 172 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

MeSH Entry Terms：

Citrocil

Dihydrostreptomycin sulfate Use and Manufacturing

Uses

antibacterial, tuberculostatic

Manufacturing Info：

D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3): INACTIVE

Use Classification：

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Computed Properties

Molecular Weight:1461.4
Hydrogen Bond Donor Count:32
Hydrogen Bond Acceptor Count:42
Rotatable Bond Count:18
Exact Mass:1460.4647787
Monoisotopic Mass:1460.4647787
Topological Polar Surface Area:928
Heavy Atom Count:95
Complexity:993
Defined Atom Stereocenter Count:30
Covalently-Bonded Unit Count:5
Compound Is Canonicalized:Yes

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Dihydrostreptomycin sulfate CAS: 5490-27-7 Dihydrostreptomycin sulfate dihydrostreptomycin solution DIHYDROSTREPTOMYCINSULPHATE(INJ.)

CAS No.: 5490-27-7

Grade: Chemical Grade

Content: 99%

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Guide of Dihydrostreptomycin sulfate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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