4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one
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4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one
structure -
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CAS No:
80841-78-7
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Formula:
C5H5ClO3
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Chemical Name:
4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one
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Synonyms:
1,3-Dioxol-2-one,4-(chloromethyl)-5-methyl-;4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one;4-Chloromethyl-5-methyl-2-oxo-1,3-dioxole;(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl chloride;4-(Chloromethyl)-5-methyldioxol-2-one
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CAS No:
Safety Information
3
22-36/37/38
26
Xn
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H302
4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one Use and Manufacturing
4725 g of dichloroethane was added to the DMDO that was stirred up.1012.5g N-chlorosuccinimideAnd 45g benzoyl peroxide, Reaction temperature 90°C, reaction time 5.5h, The crude product obtained DMDO-Cl 382.5g, a yield of 85.00percent;
4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.
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4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one
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