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N,N′-Diacetyl-L-cystine

N,N′-Diacetyl-L-cystine structure

CAS No:
5545-17-5
Formula:
C10H16N2O6S2
Chemical Name:
N,N′-Diacetyl-L-cystine
Synonyms:
L-Cystine,N,N′-diacetyl-;Cystine,N,N′-diacetyl-,L-;Cystine,N,N′-diacetyl-;N,N′-Diacetyl-L-cystine;N,N′-Diacetylcystine;NSC 203780
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits[1][2].

N,N′-Diacetyl-L-cystine Basic Attributes

Molecular Weight：

324.37

Exact Mass：

324.044983

EC Number：

226-911-5

HScode：

29225090

Characteristics

PSA：

183

XLogP3：

-0.4

Appearance：

White Powder

Density：

1.5±0.1 g/cm3

Melting Point：

273-275 °C

Boiling Point：

715.5°C at 760 mmHg

Flash Point：

386.5±32.9 °C

Refractive Index：

1.583

Storage Conditions：

-15°C

Safety Information

Stability/Shelf Life：

Moisture Sensitive

N,N′-Diacetyl-L-cystine Use and Manufacturing

N,N’-Diacetyl-L-cystine (DiNAC) is a disulfide dimer of N-acetylcysteine with immunomodulatory properties. Its intact disulfide bridge has been shown to be important for its ability to modify contact sensitivity/delayed hypersensitivity reactions in mice. At 3 μM/kg/day, DiNAC also demonstrates anti-atherosclerotic effects, improving endothelial function in Watanabe heritable hyperlipidemic rabbits.

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Guide of N,N′-Diacetyl-L-cystine

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
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