Nitarsone
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Nitarsone
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CAS No:
98-72-6
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Formula:
C6H6AsNO5
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Chemical Name:
Nitarsone
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Synonyms:
Arsonic acid,As-(4-nitrophenyl)-;Benzenearsonic acid,p-nitro-;Arsonic acid,(4-nitrophenyl)-;As-(4-Nitrophenyl)arsonic acid;Nitarsone;p-Nitrobenzenearsonic acid;(4-Nitrophenyl)arsonic acid;4-Nitrobenzenearsonic acid;(p-Nitrophenyl)arsonic acid;Histostat 50;Hep-a-Stat;Histostat;Nitarson;NSC 5085;p-Nitrophenyl arsenic acid;8027-77-8
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CAS No:
Description
ChEBI: An organoarsonic acid where the organyl group is 4-nitrophenyl.
Solid
Nitarsone is an organoarsonic acid where the organyl group is 4-nitrophenyl. It has a role as an antiprotozoal drug and an agrochemical. It is a C-nitro compound and an organoarsonic acid. It derives from a phenylarsonic acid.|Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Characteristics
103.35000
Solid
>310 °C (decomp)
540.9ºC at 760mmHg
243.3ºC
Oral-rat LDL0: 100 mg/kg
Thermal decomposition of toxic nitrogen oxides and arsenide gases
Safety Information
6.1
UN34656.1/PG3
3
23/25-50/53
20/21-28-45-60-61
CY6125000
T,N
The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials
P261-P273-P301 + P310-P311-P501
H301 + H331-H410
|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P321, P330, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Nitarsone Use and Manufacturing
Obtained by diazotization and arsine of p-nitroaniline. Add p-nitroaniline to hydrochloric acid, stir for 2h, put ice cubes to cool to -5℃, add sodium nitrite solution within 15min, and stir for about 1h to obtain diazonium salt solution. Dissolve arsenic trioxide and sodium carbonate in water, cool to below 25 ℃, add copper sulfate solution, and then add the above diazonium salt solution, the reaction temperature is controlled below 25 ℃, which can generate p-nitrophenylarsinic acid.
vasodilator (coronary)
Computed Properties
Molecular Weight:247.04
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:246.946192
Monoisotopic Mass:246.946192
Topological Polar Surface Area:103
Heavy Atom Count:13
Complexity:236
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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