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Home > Encyclopedia > N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride

N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride

N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride structure

N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride 

structure
  • CAS No:

    911-77-3

  • Formula:

    C19H22N6O4.ClH

  • Chemical Name:

    N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride

  • Synonyms:

    Benzamide,N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]-,hydrochloride (1:1);Valeranilide,2-benzamido-5-guanidino-4′-nitro-,monohydrochloride,DL-;Benzamide,N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]-,monohydrochloride,(±)-;Benzamide,N-[4-[(aminoiminomethyl)amino]-1-[[(4-nitrophenyl)amino]carbonyl]butyl]-,monohydrochloride;Nα-Benzoyl-DL-arginine-p-nitroanilide hydrochloride;NSC 83264;N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride;99671-52-0;37039-24-0

  • Categories:

    Organic Chemistry  >  Amides

Description

Light yellow fine crystalline powder


A chromogenic substrate that permits direct measurement of peptide hydrolase activity, e.g., papain and trypsin, by colorimetry. The substrate liberates p-nitroaniline as a chromogenic product.

N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride Basic Attributes

434.88

434.146942

213-011-2

29252900

Characteristics

165.92000

4.57520

White to off-white Powder

1.37g/cm3

~275 °C (dec.)

−20°C

Safety Information

NONH for all modes of transport

3

22-24/25

Drug Information

Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens). (See all compounds classified as Chromogenic Compounds.)

BAPNA

N-α-Benzoyl-DL-arginine-p-nitroanilide hydrochloride Use and Manufacturing

Substrate for trypsin, papain, ficin, bromelain, plasmin, and cathepsin B.

Computed Properties

Molecular Weight:434.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:434.1469309
Monoisotopic Mass:434.1469309
Topological Polar Surface Area:168
Heavy Atom Count:30
Complexity:588
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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