ι-Carrageenan
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ι-Carrageenan
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CAS No:
9062-07-1
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Chemical Name:
ι-Carrageenan
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Synonyms:
ι-Carrageenan;Eucheuma spinosum gum;ι-Carrageenin;Aubygel X 52;Gelcarin SI;Pellugel ID;β-Carrageenan 2,4′-bis(hydrogen sulfate);Viscarin SD 309;Soageena MV 220;Soageena MV 201;Soageena MV 320;Soageena MV 330;Carrageenan CSI 1;CSI 1;Viscarin ME 389;Hygel SI 230;Gelcarin ME 389;Gelcarin ME 621;Gelcarin GP 3367;Genuvisco X 0908;Deltagel 552;SeaSpen PF;Genuvisco JJ;Gelcarin DG 3252;Gelrich 3;CS 552;Genuvisco J;Genuvisco PJ;Satiagel 550;Meyprosol 02.2001;Aquagel I 2;Frimulsion D 021;SP 100;TS 150;SP 100 (polysaccharide);Satiagel SIA;GJ 500;Gelcarin GP 359;Newgelin GJ 500;Satiagel USC 150;Vicarin SD 389;C 1138;Sigma C 1138;C 1138 (polysaccharide);Genuvisco CL 123;Deltagel S 200;Benvisco SI 100;ι-Carrageenan C1;ι-Carrageenan C3;MV 210;Genuvisco CF 02;PJ-JPE;San Support P 190;Genuvisco TPC 1;9079-01-0
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CAS No:
Characteristics
503.69000
-1.53
White to Pale Brown Powder
Partially soluble in water, soluble in hot water. Insoluble in ethanol, in hot concentrated salt solutions.
ι-Carrageenan Use and Manufacturing
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-,and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Computed Properties
Molecular Weight:946.8
XLogP3:-9.4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:31
Rotatable Bond Count:12
Exact Mass:945.9966890
Monoisotopic Mass:945.9966890
Topological Polar Surface Area:504
Heavy Atom Count:59
Formal Charge:-4
Complexity:1840
Defined Atom Stereocenter Count:20
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It reduces the content of malondialdehyde (MDA) in rabbits with chronic intraocular hypertension, increases the activity of superoxide dismutase (SOD), and reduces the permeability of retinal blood vessels; it improves the grayscale of retinal ganglion cells and the density of active ganglion cells with high cytochrome oxidase activity in rats with acute intraocular hypertension.
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