TUFTSIN
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TUFTSIN
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CAS No:
9063-57-4
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Formula:
C21H40N8O6
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Chemical Name:
TUFTSIN
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Synonyms:
TUFTSIN;Taftsin;THR-LYS-PRO-ARG;TUFTSIN 2ACOH 4H2O;H-Thr-Lys-Pro-Arg-OH;THR-LYS-PRO-ARG 2ACOH 4H2O;L-Thr-L-Lys-L-Pro-L-Arg-OH;Tuftsin hydrate acetate salt;Tuftsin Tuftsin acetate salt hydrate
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CAS No:
Description
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
Drug Information
Biologically active substances whose activities affect or play a role in the functioning of the immune system. (See all compounds classified as Immunologic Factors.)
L-Thr-L-Lys-L-Pro-L-Arg
Computed Properties
Molecular Weight:500.6
XLogP3:-7
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:15
Exact Mass:500.30708103
Monoisotopic Mass:500.30708103
Topological Polar Surface Area:253
Heavy Atom Count:35
Complexity:760
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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