GLUCAGON HYDROCHLORIDE(HUMAN)
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GLUCAGON HYDROCHLORIDE(HUMAN)
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CAS No:
9007-92-5
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Formula:
C153H226ClN43O49S
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Chemical Name:
GLUCAGON HYDROCHLORIDE(HUMAN)
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Synonyms:
Hyperglycemic-glycogenolytic factor;l-l-alpha-aspartyl-l-seryl-l-arginyl-l-arginyl-l-alanyl-l-glutaminyl-l-alpha-a;spartyl-l-phenylalanyl-l-valyl-l-glutaminyl-l-tryptophyl-l-leucyl-l-methionyl-;threonyl-l-seryl-l-alpha-aspartyl-l-tyrosyl-l-seryl-l-lysyl-l-tyrosyl-l-leucy;GLUCAGON HYDROCHLORIDE(HUMAN);glucagon[pig];glukagonnovo;his-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-a
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CAS No:
Description
GlucaGon, a recombinant DNA product, was developed as a nasal formulation of glucagon for the treatment of insulin-induced hypoglycemia. Glucagon is widely used by insulin dependent diabetic patients as an emergency treatment for severe hypoglycemic reactions. Use of genetically engineered glucagon by both intranasal and intramuscular methods has a similar effect on hepatic glucose production rate as natural glucagon from pancreatic extraction.
GLUCAGON HYDROCHLORIDE(HUMAN) Use and Manufacturing
Glucagon is a hormone secreted by the pancreas that raises blood glucose levels. Glucagonis released by the pancreas when blood sugar (glucose) levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose thus increasing glucose levels and having the opposite effect of insulin.
Computed Properties
Molecular Weight:3482.7
XLogP3:-16.9
Hydrogen Bond Donor Count:55
Hydrogen Bond Acceptor Count:55
Rotatable Bond Count:115
Exact Mass:3481.6190567
Monoisotopic Mass:3480.6157019
Topological Polar Surface Area:1560
Heavy Atom Count:246
Complexity:8160
Defined Atom Stereocenter Count:31
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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