Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > Strychnidin-10-one, nitrate (1:1)

Strychnidin-10-one, nitrate (1:1)

Strychnidin-10-one, nitrate (1:1) structure

Strychnidin-10-one, nitrate (1:1) 

structure
  • CAS No:

    66-32-0

  • Formula:

    C21H22N2O2.HNO3

  • Chemical Name:

    Strychnidin-10-one, nitrate (1:1)

  • Synonyms:

    Strychnidin-10-one,nitrate (1:1);Strychnine,mononitrate;Strychnidin-10-one,mononitrate;4,6-Methano-6H,14H-indolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinoline,strychnidin-10-one deriv.;Strychnine nitrate

  • Categories:

    Active Pharmaceutical Ingredients  >  Nervous System Drugs

Description

An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.

Strychnidin-10-one, nitrate (1:1) Basic Attributes

397.42

397.16400

200-627-1

O642E96711

Characteristics

98.83000

2.27090

1.6270

295 °C

634.3ºC at 760 mmHg

337.4ºC

Oral-Rat  LD50 16.2  mg/kg; Oral-Mouse LD50: 0.93 mg/kg

Combustible; Fire breaks down toxic nitrogen oxide fumes

Safety Information

I

6.1(a)

UN 1692 6.1/PG 1

3

26/27/28-50/53-26/28

22-36/37/39-45-61-60-28-13

WL2450000

T+,N

Treasury is low temperature, ventilated, dry; stored separately from food raw materials

|Danger|H300 (97.56%): Fatal if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P271, P273, P284, P301+P310, P304+P340, P310, P320, P321, P330, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 41 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H300: Fatal if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P301+P310, P307+P311, P321, P330, P405, and P501

Toxicity

most toxic

Drug Information

Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools. (See all compounds classified as Convulsants.)|Substances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Glycine Agents.)|Substances which, when ingested, inhaled, or absorbed, or when applied to, injected into, or developed within the body in relatively small amounts may, by their chemical action, cause damage to structure or disturbance of function. (From Dorland, 27th ed) (See all compounds classified as Poisons.)

Nitrate, Strychnine

Computed Properties

Molecular Weight:397.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Exact Mass:397.16377084
Monoisotopic Mass:397.16377084
Topological Polar Surface Area:98.8
Heavy Atom Count:29
Complexity:714
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.