DL-Ethionine
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DL-Ethionine
structure -
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CAS No:
67-21-0
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Formula:
C6H13NO2S
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Chemical Name:
DL-Ethionine
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Synonyms:
Homocysteine,S-ethyl-;Butyric acid,2-amino-4-(ethylthio)-,DL-;DL-Homocysteine,S-ethyl-;Butyric acid,α-amino-γ-(ethylmercapto)-;S-Ethylhomocysteine;(±)-Ethionine;DL-Ethionine;DL-2-Amino-4-(ethylthio)butyric acid;CN 8676;NSC-751;dl-Ethionine;S-Ethyl-DL-homocysteine;2-Amino-4-(ethylsulfanyl)butanoic acid;2-Amino-4-ethylsulfanylbutanoic acid
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CAS No:
Description
Off-White Solid
Dl-ethionine is a white crystalline flakes. (NTP, 1992)
Dl-ethionine is a white crystalline flakes. (NTP, 1992)|S-ethylhomocysteine is a non-proteinogenic alpha-amino acid that is methionine in which the S-methyl group is replaced by an S-ethyl group. It is an organic sulfide and a non-proteinogenic alpha-amino acid.
DL-Ethionine Basic Attributes
163.24
163.24
1722529
200-647-0
97927|82393|751
DTXSID0020579
29309090
Characteristics
88.6
0.90
White to off-white Crystalline Powder or Flakes
1.2±0.1 g/cm3
265-268 °C
310℃
142℃
1.524
soluble in water.
−20°C
Slightly soluble in water.
Acids, Carboxylic
A synthetic thio-substituted amino acid.
Safety Information
NONH for all modes of transport
3
36/37/38
26
ES6825200
Xi
P261-P305 + P351 + P338
H315-H319-H335
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
|Warning|H315 (96.21%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 132 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of NOx and SOx. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
DL-Ethionine Use and Manufacturing
antineoplastic; inhibitor DNA methylation
Homocysteine, S-ethyl-: INACTIVE
Computed Properties
Molecular Weight:163.24
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:163.06669983
Monoisotopic Mass:163.06669983
Topological Polar Surface Area:88.6
Heavy Atom Count:10
Complexity:108
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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