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7-Xylosyl-10-deacetyltaxol

7-Xylosyl-10-deacetyltaxol structure

CAS No:
90332-63-1
Formula:
C50H57NO17
Chemical Name:
7-Xylosyl-10-deacetyltaxol
Synonyms:
Benzenepropanoic acid,β-(benzoylamino)-α-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,(αR,βS)-;Benzenepropanoic acid,β-(benzoylamino)-α-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.;10-Deacetyltaxol 7-xyloside;10-Deacetyl-7-xylosyltaxol;7-Xylosyl-10-deacetyltaxol;10-Deacetylpaclitaxel 7-xyloside;7β-Xylosyl-10-deacetyltaxol;10-Deacetyl-7-xylosylpaclitaxel;7-Xylosyl-10-deacetylpaclitaxel;139746-62-6;92933-58-9;181310-04-3;874910-59-5;1000777-84-3
Categories:
Natural Products > Terpenes

Description

10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.IC50 value:Target: Microtubule inhibitor10-Deacetyl-7-xylosyl paclitaxel induced mitotic cell cycle arrest and apoptosis as measured by flow cytometry, DNA laddering, and transmission electron microscopy. Pro-apoptotic Bax and Bad protein expression was up-regulated and anti-apoptotic Bcl-2 and Bcl-XL expression down-regulated, which lead to a disturbance of the

7-Xylosyl-10-deacetyltaxol Basic Attributes

Molecular Weight：

943.99

Exact Mass：

943.98

Characteristics

PSA：

274.14000

XLogP3：

7.18

Density：

1.5±0.1 g/cm3

Boiling Point：

1068.4±65.0 °C at 760 mmHg

Flash Point：

599.9±34.3 °C

Refractive Index：

1.660

Drug Information

MeSH Entry Terms：

7-xylosyl-10-deacetyl-taxol

7-Xylosyl-10-deacetyltaxol Use and Manufacturing

Anti-cancer and anti-tumor.

Computed Properties

Molecular Weight:944.0
XLogP3:0.4
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:14
Exact Mass:943.36264935
Monoisotopic Mass:943.36264935
Topological Polar Surface Area:274
Heavy Atom Count:68
Complexity:1940
Defined Atom Stereocenter Count:15
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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7-Xylosyl-10-deacetyltaxol

CAS No.: 90332-63-1

Content: 99.00%

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China Most Professional Factory Supply High Qulity 7-Xylosyl-10-deacetyltaxol CAS 90332-63-1

CAS No.: 90332-63-1

Grade: Pharmaceutical Grade

Content: 99%

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Guide of 7-Xylosyl-10-deacetyltaxol

Description
Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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7-Xylosyl-10-deacetyltaxol

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