Sarafloxacin hydrochloride
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Sarafloxacin hydrochloride
structure -
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CAS No:
91296-87-6
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Formula:
C20H17F2N3O3.ClH
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Chemical Name:
Sarafloxacin hydrochloride
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Synonyms:
3-Quinolinecarboxylic acid,6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1);3-Quinolinecarboxylic acid,6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,monohydrochloride;Sarafloxacin hydrochloride;Sarafin
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Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs
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CAS No:
Description
Sarafloxacin hydrochloride is a quinolone antibiotic drug.Target: Antibacterialsarafloxacin hydrochloride is a fluoroquinolone antibiotic registered for use against poultry diseases. Sarafloxacin treatment demonstrated mineralization to 14CO2 amounting to 0.58%, 0.49%, and 0.57% in loam, silt loam, and sandy loam soils, respectively, at the termination of the test [1]. The inhibitory level of sarafloxacin for the tested bacteria was strain dependent. It appeared that in broth culture Esc
Sarafloxacin hydrochloride Basic Attributes
421.83
421.1
1806241-263-5
I36JP4Q9DF
758956
DTXSID8045939
2933990090
Characteristics
72.9
3.57250
White to yellow crystalline solid.
1.4±0.1 g/cm3
>275 °C
621.4ºC at 760 mmHg
>110°(230°F)
1.633
soluble in water
0-6°C
1.6X10-14 mm Hg at 25 deg C (est)
185.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|199.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
3
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .
24/25
CU7700000
Xn,Xi
Stable under recommended storage conditions. /Sarafloxacin hydrochloride hydrate/
Drug Information
1-(4-fluorophenyl)-6-fluoro-7-(1-piperazinyl)-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid
Computed Properties
Molecular Weight:421.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:421.1004755
Monoisotopic Mass:421.1004755
Topological Polar Surface Area:72.9
Heavy Atom Count:29
Complexity:645
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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