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Teicoplanin A 2-2

Teicoplanin A 2-2 structure

Teicoplanin A 2-2 

structure
  • CAS No:

    91032-26-7

  • Formula:

    C88H97Cl2N9O33

  • Chemical Name:

    Teicoplanin A 2-2

  • Synonyms:

    Ristomycin A aglycone,34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(8-methyl-1-oxononyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;1H,15H,34H-20,23:30,33-Dietheno-3,18:35,48-bis(iminomethano)-4,8:10,14:25,28:43,47-tetrametheno-28H-[1,14,6,22]dioxadiazacyclooctacosino[4,5-m][10,2,16]benzoxadiazacyclotetracosine,ristomycin A aglycone deriv.;34-O-[2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(8-methyl-1-oxononyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosylristomycin A aglycone;Teicoplanin A 2-2;Teichomycin A2 factor 2;88895-83-4;91032-35-8;275826-41-0;737818-32-5

Description

White Amorphous Powder


Teicoplanin A2-2 is a teicoplanin A2 that has 8-methylnonanoyl as the variable N-acyl group. It has a role as a bacterial metabolite.

Teicoplanin A 2-2 Basic Attributes

1879.658

1879.66

9V7Z6HDK93

DTXSID30872358

Characteristics

662.41000

0.22

1.7±0.1 g/cm3

250°C (dec.)

1.754

Teicoplanin A 2-2 Use and Manufacturing

Glycopeptide antibiotic complex produced by Actinoplanes teichomyceticus; structurally related to vancomycin. Comprised of 5 major components differentiated by a specific fatty acid moiety. Inhibits peptidoglycan synthesis in the cell wall of gram-positive bacteria. Teicoplanin A2-2 is a major analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus which possesses potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis.

Computed Properties

Molecular Weight:1879.7
XLogP3:0.3
Hydrogen Bond Donor Count:24
Hydrogen Bond Acceptor Count:34
Rotatable Bond Count:19
Exact Mass:1877.5565820
Monoisotopic Mass:1877.5565820
Topological Polar Surface Area:662
Heavy Atom Count:132
Complexity:3940
Defined Atom Stereocenter Count:23
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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