A10
-
A10
structure -
-
CAS No:
91531-30-5
-
Formula:
C13H14N2O3
-
Chemical Name:
A10
-
Synonyms:
3-((phenylacetyl)amino)-2,6-piperidinedione;3-(N-phenylacetylamino)-2,6-piperidinedione;A 10;A-10;A10;antineoplaston A10;antineoplaston-A10;N-(2,6-dioxo-3-piperidinyl)benzeneacetamide;Antineoplaston A 10
-
CAS No:
Description
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.|Antineoplaston A10 is a piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04)
Computed Properties
Molecular Weight:246.26
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:246.10044231
Monoisotopic Mass:246.10044231
Topological Polar Surface Area:75.3
Heavy Atom Count:18
Complexity:348
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
- Hot Searches
- sulfuryl fluoride
- fe2o3 name
- acrolein
- cineole
- aluminum acetate
- cabr2