3'-Azido-3'-deoxythymidine-5'-triphosphate
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3'-Azido-3'-deoxythymidine-5'-triphosphate
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CAS No:
92586-35-1
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Formula:
C10H16N5O13P3·xLi
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Chemical Name:
3'-Azido-3'-deoxythymidine-5'-triphosphate
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Synonyms:
1-(3"-azido-2",3"-dideoxy-beta-D-xylofuranosyl)thymine 5"-triphosphate;3"-azido-2",3"-dideoxythymidine-5"-triphosphate;3"-azido-3"-deoxythymidine 5"-triphosphate;3"-azido-3"-deoxythymidine 5"-triphosphate, tetraammonium salt;3"-deoxy-3"-azidothymidine triphosphate;AZT triphosphate;AZT-TP;AZTTP;dTTP(3"N3);erythro-AZT-TP
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CAS No:
3'-Azido-3'-deoxythymidine-5'-triphosphate Basic Attributes
507.181
506.996
6RGF96R053
DTXSID80239053
J05AR01
Drug Information
Combivir is indicated in antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection (see section 4.2).
Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS. (See all compounds classified as Anti-HIV Agents.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)
1-(3'-azido-2',3'-dideoxy-beta-D-xylofuranosyl)thymine 5'-triphosphate
3'-Azido-3'-deoxythymidine-5'-triphosphate Use and Manufacturing
Human drugs -> Combivir -> EMA Drug Category|Antivirals for systemic use -> Human pharmacotherapeutic group|Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:507.18
XLogP3:-3.2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:9
Exact Mass:506.99574658
Monoisotopic Mass:506.99574658
Topological Polar Surface Area:233
Heavy Atom Count:31
Complexity:973
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
3'-Azido-3'-deoxythymidine-5'-triphosphate
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