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Tetramisole hydrochloride

Tetramisole hydrochloride structure

CAS No:
5086-74-8
Formula:
C11H12N2S.ClH
Chemical Name:
Tetramisole hydrochloride
Synonyms:
Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,hydrochloride (1:1);Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(±)-;Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride;McN JR 8299;R 8299;Ripercol;Tetramisole hydrochloride;(±)-Tetramisole hydrochloride;Nilverm;(±)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride;Nilverom;DL-Tetramisole hydrochloride;Anthelvet;Citarin;Concurat;Verminject;Curaminth;Tetraamisol hydrochloride;RP 16535;2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride;NSC 170985;NSC 215179;4641-34-3;13576-95-9;56720-89-9;57901-78-7;17748-90-2
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

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Description

Tetramisole hydrochloride is an inhibitor of alkaline phosphatases, is a high purity antiparasitic.

Tetramisole hydrochloride is an organic molecular entity.

Tetramisole hydrochloride Basic Attributes

Molecular Weight：

240.75

Exact Mass：

240.048798

EC Number：

225-799-5

NSC Number：

759175|758437|215179|170985

HScode：

2934100090

Characteristics

PSA：

40.9

XLogP3：

2.32160

Appearance：

white to pale cream crystalline powder

Melting Point：

264-266 °C

Boiling Point：

344.4ºC at 760 mmHg

Flash Point：

162.1ºC

Water Solubility：

H2O: 200 g/L (20 ºC)

Storage Conditions：

Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.

Toxicity：

LD50 in mice, rats (mg/kg): 22, 24 i.v.; 84, 130 s.c.; 210, 480 orally (Thienpoint)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

22-36/37/38-20/21/22

safety instructions：

26-36

RTECS Number：

NJ5950000

Marks：

Xn,Xi

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H335

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 243 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

Nilverm

Tetramisole hydrochloride Use and Manufacturing

Tetraimidazole hydrochloride is a biological response modifier with insect repellent activity. Insecticide (nematode); immune modulator. Used as an intermediate of levamisole and anti-worm medicine.

Computed Properties

Molecular Weight:240.75
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:240.0487973
Monoisotopic Mass:240.0487973
Topological Polar Surface Area:40.9
Heavy Atom Count:15
Complexity:246
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Guide of Tetramisole hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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