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Home > Encyclopedia > Tetramisole hydrochloride

Tetramisole hydrochloride

Tetramisole hydrochloride structure

Tetramisole hydrochloride 

structure
  • CAS No:

    5086-74-8

  • Formula:

    C11H12N2S.ClH

  • Chemical Name:

    Tetramisole hydrochloride

  • Synonyms:

    Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,hydrochloride (1:1);Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(±)-;Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride;McN JR 8299;R 8299;Ripercol;Tetramisole hydrochloride;(±)-Tetramisole hydrochloride;Nilverm;(±)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride;Nilverom;DL-Tetramisole hydrochloride;Anthelvet;Citarin;Concurat;Verminject;Curaminth;Tetraamisol hydrochloride;RP 16535;2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride;NSC 170985;NSC 215179;4641-34-3;13576-95-9;56720-89-9;57901-78-7;17748-90-2

  • Categories:

    Active Pharmaceutical Ingredients  >  Antiparasitic Drugs

Description

Tetramisole hydrochloride is an inhibitor of alkaline phosphatases, is a high purity antiparasitic.


Tetramisole hydrochloride is an organic molecular entity.

Tetramisole hydrochloride Basic Attributes

240.75

240.048798

225-799-5

759175|758437|215179|170985

2934100090

Characteristics

40.9

2.32160

white to pale cream crystalline powder

264-266 °C

344.4ºC at 760 mmHg

162.1ºC

H2O: 200 g/L (20 ºC)

Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.

LD50 in mice, rats (mg/kg): 22, 24 i.v.; 84, 130 s.c.; 210, 480 orally (Thienpoint)

Safety Information

NONH for all modes of transport

3

22-36/37/38-20/21/22

26-36

NJ5950000

Xn,Xi

Stable under normal temperatures and pressures.

P261-P305 + P351 + P338

H302-H315-H319-H335

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 243 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Nilverm

Tetramisole hydrochloride Use and Manufacturing

Tetraimidazole hydrochloride is a biological response modifier with insect repellent activity. Insecticide (nematode); immune modulator. Used as an intermediate of levamisole and anti-worm medicine.

Computed Properties

Molecular Weight:240.75
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:240.0487973
Monoisotopic Mass:240.0487973
Topological Polar Surface Area:40.9
Heavy Atom Count:15
Complexity:246
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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