β-Amyrin
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β-Amyrin
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CAS No:
559-70-6
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Formula:
C30H50O
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Chemical Name:
β-Amyrin
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Synonyms:
Olean-12-en-3-ol,(3β)-;Olean-12-en-3β-ol;(3β)-Olean-12-en-3-ol;β-Amyrenol;β-Amyrin;β-Amyrine;3β-Hydroxyolean-12-ene;(+)-β-Amyrin;β-Amirin;NSC 527971
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CAS No:
Description
β-Amyrin, an ingredient of the surface wax of tomato fruit and dandelion coffee, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1].
Beta-amyrin is a pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants. It has a role as a plant metabolite and an Aspergillus metabolite. It is a pentacyclic triterpenoid and a secondary alcohol. It derives from a hydride of an oleanane.
Characteristics
20.2
11.06
1.0±0.1 g/cm3
197 °C
bp0.8 260°
217.7±20.7 °C
1.539
D19 +99.8° (c = 1.3 in benzene)
Safety Information
NONH for all modes of transport
3
22
22-45
Xi
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory.
β-Amyrin Use and Manufacturing
nociceptive
Lipids -> Prenol Lipids [PR] -> Isoprenoids [PR01] -> C30 isoprenoids (triterpenes) [PR0106]
Computed Properties
Molecular Weight:426.7
XLogP3:9.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:426.386166214
Monoisotopic Mass:426.386166214
Topological Polar Surface Area:20.2
Heavy Atom Count:31
Complexity:790
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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