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Home > Encyclopedia > 7-Aminoindole

7-Aminoindole

7-Aminoindole structure

7-Aminoindole 

structure
  • CAS No:

    5192-04-1

  • Formula:

    C8H8N2

  • Chemical Name:

    7-Aminoindole

  • Synonyms:

    7-Indolamine;7-AMINOINDOLE;7-Indolylamine;1H-Indol-7-amine;(Indol-7-yl)amine;7-Amino-1H-indole;1H-INDOL-7-YLAMINE;7-Amino-1H-indole97%;7-Aminoindole5192-4-1;7-AMinoindole,>=95.0%(HPLC)

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

1H-indol-7-amine is an indolamine.

7-Aminoindole Basic Attributes

132.16

132.06900

471787

-0

DTXSID30276110

2933990090

Characteristics

41.8

2.1

1.268g/cm3

96-100 °C

354ºC at 760mmHg

195ºC

1.757

Keep Cold

Safety Information

III

NONH for all modes of transport

3

36/37/38

26-36

Xi

Harmful/Irritant/Keep Cold

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H302 (15.56%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 45 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

1-aminoindole

7-Aminoindole Use and Manufacturing

Reactant for preparation of:• ;Fluorescent anion receptors and sensors1,2• ;Sulfate receptors3• ;Protein Kinase C θ (PKCθ) inhibitors4• ;Factor Xa Inhibitors5• ;Aurora kinase inhibitor• ;Antagonist of Mineralocorticoid Receptor6• ;Potent histone deacetylase (HDAC) inhibitors7• ;TRPV1 antagonists8• ;Derivatives of N-(7-indolyl)benzenesulfonamide as cell cycle inhibitors9

Computed Properties

Molecular Weight:132.16
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Exact Mass:132.068748264
Monoisotopic Mass:132.068748264
Topological Polar Surface Area:41.8
Heavy Atom Count:10
Complexity:124
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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