 Home > Encyclopedia > 2,5-Dibromobenzoic acid

2,5-Dibromobenzoic acid

2,5-Dibromobenzoic acid structure

CAS No:
610-71-9
Formula:
C7H4Br2O2
Chemical Name:
2,5-Dibromobenzoic acid
Synonyms:
Benzoic acid,2,5-dibromo-;2,5-Dibromobenzoic acid;NSC 190697
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Request for Quotation

Description

off-white powder

2,5-Dibromobenzoic acid Basic Attributes

Molecular Weight：

279.91

Exact Mass：

279.91

EC Number：

210-234-7

UNII：

AL6IIX5WZY

NSC Number：

190697

DSSTox ID：

DTXSID30209862

HScode：

2916399090

Characteristics

PSA：

37.3

XLogP3：

3.7

Appearance：

white to off white crystal powder

Density：

2.1±0.1 g/cm3

Melting Point：

157 °C

Boiling Point：

344.6°C at 760 mmHg

Flash Point：

162.2±25.1 °C

Refractive Index：

1.643

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R36/37/38

safety instructions：

S26-S36

RTECS Number：

DG6290000

Marks：

Xi:Irritant;

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 49 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2,5-Dibromobenzoic acid Use and Manufacturing

First, sodium periodate solution was configured: 4.3 g (19.9 mmol) of sodium periodate was dissolved in 30 ml of water and 18 ml of acetic acid.Then, 10 g (49.7 mmol) of 2-bromobenzoic acid, 5.1 g (49.7 mmol) of sodium bromide, and sodium periodate solution were added to the reaction flask.Heat to 30°C and add 4.4 ml concentrated sulfuric acid slowly at this temperature.After completion of the dropwise addition of concentrated sulfuric acid, the temperature was raised to 50-65°C and reacted at this temperature for 2-3 hours.Thin layer chromatography (TLC) detection reaction is completed, cooled, poured into ice water, solid precipitated, filtered, The filter cake was washed with water several times to obtain 11.9 g of 2, 5-dibromobenzoic acid in a yield of 85.6percent.

Computed Properties

Molecular Weight:279.91
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:279.85576
Monoisotopic Mass:277.85780
Topological Polar Surface Area:37.3
Heavy Atom Count:11
Complexity:161
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2,5-Dibromobenzoic acid

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

2,5-Dibromobenzoic acid.

CAS No.: 610-71-9

Content: 98%

Inquiry
QUANHUI BIO Contact Supplier

CN
1 YR

Business licensed

Trader Supplier of API & INTERMEDIATE

2,5-Dibromobenzoic acid

Unit Price: $100 /KG EXW

CAS No.: 610-71-9

Grade: Pharmaceutical Grade

Content: 99%

Inquiry