 Home > Encyclopedia > Amobarbital sodium

Amobarbital sodium

Amobarbital sodium structure

CAS No:
64-43-7
Formula:
C11H18N2O3.Na
Chemical Name:
Amobarbital sodium
Synonyms:
2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-(3-methylbutyl)-,sodium salt (1:1);Barbituric acid,5-ethyl-5-isopentyl-,sodium salt;2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-(3-methylbutyl)-,monosodium salt;Barbituric acid,5-ethyl-5-isopentyl-,sodium deriv.;Alitinal;Amobarbital sodium;Amylobarbitone sodium;Amytal sodium;t-Barb;Dorminal;Dusotal;Sodium 5-ethyl-5-isopentylbarbiturate;Sodium amobarbital;Sodium amylobarbitone;Sodium Barbamyl;Sodium ethylisoamylbarbiturate;Sodium isoamylethylbarbiturate;Barbamyl;Sodium Amytal;Sodium amylobarbital;Inmetal;Amsebarb;Barbamil;Isomytal sodium;Ambarlone;Amiotal;S. P. Amobarb;Hypnobal;Sodium 5-ethyl-5-(3-methylbutyl)barbiturate;Dormital;Sodium amital;Iosmytal sodium;Talamo;35942-73-5
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

Request for Quotation

Amobarbital sodium Basic Attributes

Molecular Weight：

248.26

Exact Mass：

248.113693

EC Number：

200-584-9

Characteristics

PSA：

81.59000

XLogP3：

1.02630

Flash Point：

11 °C

Storage Conditions：

2-8°C

Toxicity：

Oral-rat LD50: 275 mg/kg; Oral-Mouse LD50: 505 mg/kg

Flammability characteristics：

Yes; burning produces toxic nitrogen oxides and sodium oxide fumes

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

22-39/23/24/25-23/24/25-11

safety instructions：

36-45-36/37-16-7

RTECS Number：

CQ5250000

Marks：

Xn,T,F

Storage features：

Warehouse ventilated, low temperature and dry

Precautionary statement(s)：

Missing Phrase - N15.00950417

Hazard Statements：

H301

Toxicity

Toxicity class：

highly toxic

Amobarbital sodium Use and Manufacturing

Methods of Manufacturing

It is derived from the salt of isopentobarbital (see 02870). Prepare the ethanol solution of sodium hydroxide first, dissolve the isoamtobarbital in the ethanol solution of sodium hydroxide, add activated carbon, and decolorize for half an hour under stirring at room temperature. The activated carbon is filtered off, and the filtrate is distilled under reduced pressure to recover ethanol. Acetone was added to crystallize the sodium isoamylbarbitone. Filter and dry under reduced pressure to obtain the product with a yield of 70%.

Uses

This product is a hypnotic for medium time.