6-CHLORO(1H)INDAZOLE
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6-CHLORO(1H)INDAZOLE
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CAS No:
698-25-9
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Formula:
C7H5ClN2
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Chemical Name:
6-CHLORO(1H)INDAZOLE
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Synonyms:
6-Chloro-1H-indazole;6-Chloroindazole;1H-Indazole, 6-chloro-;1H-INDAZOLE,6-CHLORO-;CHEMBL392184;6-chloroazaindole;6-chloro-indazole;NSC92743;PubChem20592;SCHEMBL3533806
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CAS No:
Safety Information
Xn
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
6-CHLORO(1H)INDAZOLE Use and Manufacturing
General procedure: NaNO6-Chloroindazole. A solution of 4-chloro-2-fluorobenzaldehyde (5.0 g, 31.6 mmol) in 12 mL of pyridine was treated with hydrazine hydrate (10 eq., 10 mL) and DMAP (3.85 g, 31.6 mmol) and the mixture heated to 100 °C for several hours. The mixture was allowed to cool to RT and was diluted with EtOAc and washed several times with dilute acid. The EtOAc solution was dried over MgS0