3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)
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3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)
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CAS No:
6027-91-4
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Formula:
C6H9NO2.ClH
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Chemical Name:
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)
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Synonyms:
3-Pyridinecarboxylic acid,1,2,5,6-tetrahydro-,hydrochloride (1:1);Nicotinic acid,1,2,5,6-tetrahydro-,hydrochloride;Guvacine,hydrochloride;3-Pyridinecarboxylic acid,1,2,5,6-tetrahydro-,hydrochloride;1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride
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CAS No:
Description
Guvacine hydrochloride is an alkaloid from the nut of Areca catechu, acts as an inhibitor of GABA transporter, and dispalys modest selectivity for cloned GABA transporters with IC50s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3).
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1) Basic Attributes
163.60200
163.04000
2933399090
Safety Information
NONH for all modes of transport
3
36/37/38
26-36
Xi
P261-P305 + P351 + P338
H315-H319-H335
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1) Use and Manufacturing
Guvacine Hydrochloride is a GABA uptake inhibitor and it is used for the treatment of neurodegenerative diseases.
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3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)
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