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α-Methyl-p-tyrosine

α-Methyl-p-tyrosine structure

CAS No:
658-48-0
Formula:
C10H13NO3
Chemical Name:
α-Methyl-p-tyrosine
Synonyms:
Tyrosine,α-methyl-;α-Methyltyrosine;α-Methyl-p-tyrosine;DL-α-Methyltyrosine;DL-α-Methyl-p-tyrosine;α-MPT;(±)-α-Methyl-p-tyrosine;DL-2-Methyl-p-tyrosine;α-Methyl-DL-tyrosine;Racemetirosine;dl-Metyrosine;2-(4-Hydroxybenzyl)-2-aminopropanoic acid;L 1-79;SM 88;(±)-α-Methyl-DL-tyrosine;2-Amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid;2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid;620-30-4;2304018-89-9
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

off-white fine powder

An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)

α-Methyl-p-tyrosine Basic Attributes

Molecular Weight：

195.21512

Exact Mass：

195.22

EC Number：

211-523-0

HScode：

2922509090

Characteristics

PSA：

83.6

XLogP3：

-1.6

Appearance：

off-white fine powder

Density：

1.3±0.1 g/cm3

Melting Point：

>300 °C

Boiling Point：

383.7°C at 760 mmHg

Flash Point：

185.9±25.1 °C

Refractive Index：

1.600

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

RTECS Number：

YP2890000

Drug Information

MeSH：

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

MeSH Entry Terms：

alpha Methyl p tyrosine

α-Methyl-p-tyrosine Use and Manufacturing

Uses

A tyrosine hydroxylase inhibitor.An antihypertensive in pheochromocytoma.

Manufacturing Info：

Tyrosine, .alpha.-methyl-: INACTIVE

Computed Properties

Molecular Weight:195.21
XLogP3:-1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:195.08954328
Monoisotopic Mass:195.08954328
Topological Polar Surface Area:83.6
Heavy Atom Count:14
Complexity:211
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of α-Methyl-p-tyrosine

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DL-alpha-Methyltyrosine

CAS No.: 658-48-0

Content: 99.00%

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Guide of α-Methyl-p-tyrosine

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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α-Methyl-p-tyrosine

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