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A-METHYL-DL-P-TYROSINE

A-METHYL-DL-P-TYROSINE structure

CAS No:
658-48-0
Formula:
C10H13NO3
Chemical Name:
A-METHYL-DL-P-TYROSINE
Synonyms:
(2R)-2-ammonio-3-(4-hydroxyphenyl)-2-methylpropanoate;A-METHYL-DL-P-TYROSINE;alpha-methyl-para-tyrosine;alpha-methyl-p-tyrosine;alpha-methyl-tyrosin;h9/88;DL-α-Methyltyrosine;2-P-HYDROXYPHENYLMETHYL-DL-ALANINE
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

off-white fine powder

An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)

A-METHYL-DL-P-TYROSINE Basic Attributes

Molecular Weight：

195.22

Exact Mass：

195.22

BRN：

2938704

EC Number：

211-523-0

TSCA：

TSCA listed

Color/Form：

White to Off-White

HScode：

29225000

Characteristics

PSA：

83.6

XLogP3：

-1.6

Appearance：

off-white fine powder

Density：

1.1926 (rough estimate)

Melting Point：

>300 °C(lit.)

Boiling Point：

331.88°C (rough estimate)

Flash Point：

185.9±25.1 °C

Refractive Index：

1.5150 (estimate)

Storage Conditions：

−20°C

PKA：

2.29±0.16(Predicted)

Critical Temperature & Pressure：

Keep in dark place,Sealed in dry,Room Temperature

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

RTECS Number：

YP2890000

Drug Information

MeSH：

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

MeSH Entry Terms：

alpha Methyl p tyrosine

A-METHYL-DL-P-TYROSINE Use and Manufacturing

Uses

A tyrosine hydroxylase inhibitor.An antihypertensive in pheochromocytoma.

peptide synthesis

Manufacturing Info：

Tyrosine, .alpha.-methyl-: INACTIVE

Computed Properties

Molecular Weight:195.21
XLogP3:-1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:195.08954328
Monoisotopic Mass:195.08954328
Topological Polar Surface Area:83.6
Heavy Atom Count:14
Complexity:211
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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DL-alpha-Methyltyrosine

CAS No.: 658-48-0

Content: 99.00%

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Guide of A-METHYL-DL-P-TYROSINE

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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A-METHYL-DL-P-TYROSINE

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