D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2)
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D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2)
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CAS No:
6055-82-9
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Formula:
C6H14O12P2.2Ca
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Chemical Name:
D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2)
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Synonyms:
D-Fructose,1,6-bis(dihydrogen phosphate),calcium salt (1:2);Fructose,1,6-diphosphate,dicalcium salt,D-;Calcium fructose diphosphate;Candiolin;23684-52-8;25584-82-1
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CAS No:
D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2) Basic Attributes
416.24
415.889923
227-979-9
R0SR7425RJ
29400090
D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2) Use and Manufacturing
D-Fructose 1,6-Biphosphate is essential for glycolysis to occur efficiently. It links to adenine nucleotides which regulate 6-phosphofructokinases (Pfks) that catalyze one of the rate limiting steps of glycolysis. This is the dicalcium salt.
D-Fructose, 1,6-bis(dihydrogen phosphate), calcium salt (1:2): INACTIVE
Computed Properties
Molecular Weight:416.24
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:7
Exact Mass:415.8899314
Monoisotopic Mass:415.8899314
Topological Polar Surface Area:223
Heavy Atom Count:22
Complexity:387
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
This product is an intermediate product in the process of glucose metabolism. Exogenous fructose diphosphate can act on the cell membrane, and by activating phosphofructokinase on the cell membrane, it increases the concentration of high-energy phosphate bonds and adenosine triphosphate in the cell, thereby promoting the influx of potassium ions, restoring the cell's resting state, increasing the content of diphosphoglycerate in red blood cells, and inhibiting the release of oxygen free radicals and histamine. It is beneficial to the cell energy metabolism and the utilization of glucose in states of shock, ischemia, hypoxia, tissue damage, extracorporeal circulation, blood transfusion, etc., and promotes repair and improves cell function.
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