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Home > Encyclopedia > N-Acetoxy-N-acetyl-2-aminofluorene

N-Acetoxy-N-acetyl-2-aminofluorene

N-Acetoxy-N-acetyl-2-aminofluorene structure

N-Acetoxy-N-acetyl-2-aminofluorene 

structure
  • CAS No:

    6098-44-8

  • Formula:

    C17H15NO3

  • Chemical Name:

    N-Acetoxy-N-acetyl-2-aminofluorene

  • Synonyms:

    Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-;Hydroxylamine,N,O-diacetyl-N-fluoren-2-yl-;N-(Acetyloxy)-N-9H-fluoren-2-ylacetamide;N-Acetoxy-N-2-fluorenylacetamide;N-Acetyl-N-acetoxy-2-aminofluorene;N-Acetoxy-N-acetyl-2-aminofluorene;2-(Acetoxyacetylamino)fluorene;N-Acetoxy-2-acetamidofluorene;N-Acetoxy-2-(acetylamino)fluorene;N-Acetyloxy-2-acetylaminofluorene;N-Acetoxy-N-acetamidofluorene;2-(N-Acetoxyacetamido)fluorene;NSC 163627

Description

ChEBI: A 2-acetamidofluorene compound in which the parent 2-acetamidofluorene is substitued on nitrogen by an acetoxy group


N-acetoxy-2-acetamidofluorene is a 2-acetamidofluorene compound in which the parent 2-acetamidofluorene is substituted on nitrogen by an acetoxy group. It has a role as a carcinogenic agent and a mutagen.|An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.

N-Acetoxy-N-acetyl-2-aminofluorene Basic Attributes

281.3059

281.31

163627

DTXSID90209828

Characteristics

46.6

3

1.1302 (rough estimate)

mma-sat 1500 ng/plate CBINA8 54,71,85

Flammable; decomposes by heating to release toxic nitrogen oxide fumes

Safety Information

Warehouse ventilated, low temperature and dry

Drug Information

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. (See all compounds classified as Alkylating Agents.)

Acetoxyacetamidofluorene

Computed Properties

Molecular Weight:281.30
XLogP3:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:281.10519334
Monoisotopic Mass:281.10519334
Topological Polar Surface Area:46.6
Heavy Atom Count:21
Complexity:422
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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