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Ursonic acid

Ursonic acid structure

Ursonic acid 

structure
  • CAS No:

    6246-46-4

  • Formula:

    C30H46O3

  • Chemical Name:

    Ursonic acid

  • Synonyms:

    Urs-12-en-28-oic acid,3-oxo-;3-Oxours-12-en-28-oic acid;Ursonic acid;3-Ketoursolic acid;142382-35-2

  • Categories:

    Natural Products  >  Terpenes

Description

Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. In vitro: Ursolic acid is important in the induction of apoptosis via AKT/NF-κB signaling suppression in T24 human bladder cancer cells and this occurs in a dose-dependent manner. Thus, Akt and NF-κB are potential targets for bladder cancer therapy and ursolic acid may serve as a naturally-occurring candidate drug for the prevention and treatment of bladder c


Ursonic acid is a triterpenoid.

Ursonic acid Basic Attributes

454.68

454.68

2918300090

Characteristics

54.37000

8.43

1.1±0.1 g/cm3

284-285 °C

555.1±50.0 °C at 760 mmHg

303.6±26.6 °C

1.550

Drug Information

ursonic acid

Computed Properties

Molecular Weight:454.7
XLogP3:7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:454.34469533
Monoisotopic Mass:454.34469533
Topological Polar Surface Area:54.4
Heavy Atom Count:33
Complexity:916
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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