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2-Ethoxy-5-methylaniline

2-Ethoxy-5-methylaniline structure

2-Ethoxy-5-methylaniline 

structure
  • CAS No:

    6331-70-0

  • Formula:

    C9H13NO

  • Chemical Name:

    2-Ethoxy-5-methylaniline

  • Synonyms:

    Benzenamine,2-ethoxy-5-methyl-;o-Phenetidine,5-methyl-;2-Ethoxy-5-methylbenzenamine;2-Ethoxy-5-methylaniline;NSC 37005

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

2-Ethoxy-5-methylaniline Basic Attributes

151.20562

151.21

228-708-7

37005

2922299090

Characteristics

35.2

2.1

1.018g/cm3

40-41 °C

252.5°C at 760 mmHg

109.2ºC

1.54

2-Ethoxy-5-methylaniline Use and Manufacturing

A suspension of 1-ethoxy-4-methyl-2-nitro-benzene (2.71 g) obtained in Example (41a) and a 10percent palladium-carbon catalyst (0.27 g) in anhydrous tetrahydrofuran (40 mL) was stirred at room temperature under a hydrogen atmosphere for 25.5 hours. The reaction mixture was filtered through a cellulose powder, concentrated and dried under reduced pressure, and 2.26 g (100percent) of the title compound was obtained as a dark brown solid.

Computed Properties

Molecular Weight:151.21
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:151.099714038
Monoisotopic Mass:151.099714038
Topological Polar Surface Area:35.2
Heavy Atom Count:11
Complexity:116
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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