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6α-Hydroxyestrone

6α-Hydroxyestrone structure

6α-Hydroxyestrone 

structure
  • CAS No:

    1476-78-4

  • Formula:

    C18H22O3

  • Chemical Name:

    6α-Hydroxyestrone

  • Synonyms:

    Estra-1,3,5(10)-trien-17-one,3,6-dihydroxy-,(6α)-;Estra-1,3,5(10)-trien-17-one,3,6α-dihydroxy-;(6α)-3,6-Dihydroxyestra-1,3,5(10)-trien-17-one;6α-Hydroxyestrone

Description

ChEBI: A 6alpha-hydroxy steroid that is estrone substituted by an alpha-hydroxy group at position 6.

6α-Hydroxyestrone Basic Attributes

286.371

286.37

740029

Characteristics

57.5

3.30830

1.249g/cm3

492.1ºC at 760mmHg

265.5ºC

1.611

Drug Information

6-hydroxyestrone

6α-Hydroxyestrone Use and Manufacturing

The oxidative 6α-metabolite of 17β-Estradiol (E887995) and Estrone (E889050) formed by 15 selectively expressed human cytochrome p450 isoforms.

Computed Properties

Molecular Weight:286.4
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Exact Mass:286.15689456
Monoisotopic Mass:286.15689456
Topological Polar Surface Area:57.5
Heavy Atom Count:21
Complexity:448
Defined Atom Stereocenter Count:4
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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