Oleoylethanolamide
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Oleoylethanolamide
structure -
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CAS No:
111-58-0
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Formula:
C20H39NO2
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Chemical Name:
Oleoylethanolamide
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Synonyms:
9-Octadecenamide,N-(2-hydroxyethyl)-,(9Z)-;Oleamide,N-(2-hydroxyethyl)-;9-Octadecenamide,N-(2-hydroxyethyl)-,(Z)-;(9Z)-N-(2-Hydroxyethyl)-9-octadecenamide;Oleic acid ethanolamide;Oleic acid monoethanolamide;N-Oleoylethanolamine;N-Oleoyl-2-aminoethanol;N-(2-Hydroxyethyl)oleamide;AM 3101;Oleamide MEA;Oleoylethanolamide;N-(2-Hydroxyethyl)-9-Z-octadecenamide;N-Oleoylethanolamide
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CAS No:
Description
ChEBI: An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide
Liquid; OtherSolid
Characteristics
49.3
6.36
Liquid; OtherSolid
0.915±0.06 g/cm3(Predicted)
63-64 °C
496.4±38.0 °C(Predicted)
254.0±26.8 °C
1.474
−20°C
6.22E-12mmHg at 25°C
Safety Information
IRRITANT
NONH for all modes of transport
2
36/37/38
26-36
Xi
P261-P305 + P351 + P338
H315-H319-H335
Oleoylethanolamide Use and Manufacturing
Lipid mediator and analog of anandamide (N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ) that is involved in peripheral regulation of feeding. Selective GPR55 agonist (EC 50 values are 0.44, >30 and >30 μ M at GPR55, CB 1 and CB 2 respectively) and PPAR α agonist (EC 50 = 120 nM). Induces satiety through activation of PPAR α and is also a ceramidase inhibitor. Also endogenous agonist at the GPR119 receptor.FAAH catalysis is based o
Surface active agents
Laundry and dishwashing products
All other basic organic chemical manufacturing|9-Octadecenamide, N-(2-hydroxyethyl)-, (9Z)-: ACTIVE
Computed Properties
Molecular Weight:325.5
XLogP3:6.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:17
Exact Mass:325.298079487
Monoisotopic Mass:325.298079487
Topological Polar Surface Area:49.3
Heavy Atom Count:23
Complexity:277
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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