Glycol monostearate
-
Glycol monostearate
structure -
-
CAS No:
111-60-4
-
Formula:
C20H40O3
-
Chemical Name:
Glycol monostearate
-
Synonyms:
Octadecanoic acid,2-hydroxyethyl ester;Stearic acid,2-hydroxyethyl ester;Ethylene glycol,monostearate;S 151;Empilan 2848;Ethylene glycol stearate;Glycol monostearate;Glycol stearate;Ivorit;Monthybase;Monthyle;Parastarin;Prodhybas N;Prodhybase ethyl;Sedetol;Tego-stearate;2-Hydroxyethyl stearate;Emerest 2350;Tegin EGMS-VA;Cutina EGMS;Kessco EGMS;Kessco EGMS 70;Nikkol EGMS 70;Emcol ES 50;Stepan EGMS;EGMS 70V;Emalex EG-M-S;8034-25-1
- Categories:
-
CAS No:
Description
Liquid|Cream-coloured flakes or waxy solid at 25 °C with a faint odour
Polyoxyl 40 stearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units. It is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier. It has a role as a nonionic surfactant, an emulsifier and a food emulsifier. It is a hydroxypolyether and an octadecanoate ester.
Glycol monostearate Basic Attributes
328.53
328.53
203-886-9
0324G66D0E
31811
DTXSID5026881|DTXSID6027715
CREAM-COLORED SOFT, WAXY OR PASTY SOLID @ 25 °C
29189900
Characteristics
46.53000
5.78340
White to pale yellow Flakes
0.913 g/cm3
60.5 °C
>400 °C
240ºC
SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL
FAINT FATTY ODOR
SLIGHTLY BITTER, FATTY TASTE
NONIONIC SURFACTANT|NEARLY ODORLESS /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/
Safety Information
60-22-36/37/38-63
24/25-45-36/37/39-28-27-26-53
WI4100000
T
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (39.22%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 448 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 313 companies from 3 notifications to the ECHA C&L Inventory.
Toxicity
MYRI 32 INCREASED GI ABSORPTION OF ORAL GENTAMICIN IN RATS.|SENSITIVITY OF FEEDING TESTS IN DETECTING CARCINOGENICITY OF SMALL DOSE OF 7,12-DIMETHYLBENZ[A]ANTHRACENE IN FEMALE RATS INCR WHEN IT WAS GIVEN AT AN EARLIER AGE AND WHEN A HIGH FAT DIET CONTAINING 1% POLYOXYETHYLENE MONOSTEARATE WAS ADMIN.
Drug Information
THESE ESTERS ARE HYDROLYZED IN THE BOWEL. THE FATTY ACID IS ABSORBED & METABOLIZED; AT LEAST THE SHORTER POLYOXYETHYLENE RESIDUES ARE ALSO ABSORBED, BUT THEY ARE EXCRETED UNCHANGED IN THE URINE (NO DETECTABLE METABOLISM TO OXALIC ACID IN MAN).
Glycol monostearate Use and Manufacturing
REACTION OF ETHYLENE OXIDE WITH STEARIC ACID
Pegosperse(R) 50 MS is a low HLB surface agent suggested for use as an opacifier, pearlescing agent and auxiliary emulsifier in cosmetic and household product formulations.
Pearlizing Agent
Cleaning and furnishing care products
(1972) 2.4X10+9 GRAMS (MONOSTEARATE)|(1975) 3.13X10+9 GRAMS (MONOSTEARATES)|(1984) 2.91X10+9 g
POLYOXYETHYLENE (8) STEARATE: MIXTURE OF MONO- & DIESTERS OF STEARIC ACID & MIXED POLYOXYETHYLENE DIOLS HAVING AN AVG POLYMER LENGTH OF 7.5 OXYETHYLENE UNITS.
All other basic organic chemical manufacturing|Octadecanoic acid, 2-hydroxyethyl ester: ACTIVE|Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).|POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI: IT IS AN ETHER, ALCOHOL & ESTER.
A sample work-up method for gas chromatographic profiling of polyethylene glycol related cmpd in pharmaceutical matrixes is described. After a short sample clean-up, carbon-oxygen linkages were partially cleaved with 0.07/M BBr3 in CH2Cl2 at room temp. The reaction was stopped after 1 min by addn of 0.01M hydrochloric acid. The products were trimethylsilylated and injected onto a WCOT 50 m X 0.25 mm CP-SIL 5 CB fused silica column. Eleven model cmpd, representing 4 common types of polyethylene glycol deriv, were evaluated by this method. Characteristic profiles can be obtained from polyethylene glycol deriv carrying different functional groups. Minimum detectable amt are in the range of 200 ug.
EPA Safer Chemical Functional Use Classes -> Surfactants|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|EPA Safer Chemical Functional Use Classes -> Defoamers;Surfactants|Food additives|Cosmetics -> Emollient; Emulsifying; Humectant; Opacifying; Surfactant
Computed Properties
Molecular Weight:328.5
XLogP3:7.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:19
Exact Mass:328.29774513
Monoisotopic Mass:328.29774513
Topological Polar Surface Area:46.5
Heavy Atom Count:23
Complexity:241
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Emollient, opacifying agent, provides pearlescent appearance in products
Recommended Suppliers of Glycol monostearate
-
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Dichloromethane,Linocaine hydrochlorideInquiryCAS No.: 111-60-4Content: 99% -
![India]()
IN
2 YRS
Business licensed Verified SupplierTrader Supplier of Chemical,API,Solvents,AcidInquiryCAS No.: 111-60-4Grade: Industrial GradeContent: 99% -
![China]()
CN
2 YRS
Business licensedTrader Supplier of Titanium dioxide,npk,pvc,sles,labsa,mdi,tdi,Ethylene glycol,p-xylene,mtbe,styrene,Ethyl alcohol,Anthracite (coke),Citric acid,carbinol,toluene,Acetic acid,Dichloroethane,PhenolInquiryCAS No.: 111-60-4Grade: Industrial GradeContent: 99% -
![China]()
CN
4 YRS
Business licensed Certified factoryManufactory Supplier of Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals,Surfactant,Food Additives,Water Treatment Chemicals -
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of chemicalsInquiryCAS No.: 111-60-4Grade: USP / EP / BP / JP GradeContent: 99%
Learn More Other Chemicals
-
Polyethylene glycol octyl ether acid phosphate
31800-88-1
-
Carboxymethyl polyethylene glycol oleyl ether
57635-48-0
-
Aniline,4,4′-methylenedi-,polymer with 1,2,4-benzenetricarboxylic acid cyclic 1,2-anhydride,dimethyl terephthalate,ethylene glycol and 1,3,5-tris(2-hydroxyethyl)-s-triazine-2,4,6(1H,3H,5H)-trione
25950-45-2
-
Urea, reaction products with ethylene glycol and ethylene oxide Formula
78355-52-9
-
Phosphoric acid, mixed esters with 2-ethyl-1-hexanol and polyethylene glycol monotridecyl ether Formula
68937-44-0
-
Benzenesulfonic acid, dodecyl-, compds. with ammonia-ethylene glycol reaction product morpholine derivs. residues Formula
68955-71-5
-
Octadecanoic acid, mixed esters with myristic acid and neopentyl glycol Structure
68585-01-3
-
(3-BROMOMETHYLPHENYL)BORONIC ACID NEOPENTYL GLYCOL ESTER Structure
143805-78-1
-
What is Methoxypolyethylene glycol succinimidyl succinate
78274-32-5
-
What is Diethylene glycol monoisobutyl ether
18912-80-6