Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > 5-Phenyl-2,4-pentadienoic acid

5-Phenyl-2,4-pentadienoic acid

5-Phenyl-2,4-pentadienoic acid structure

5-Phenyl-2,4-pentadienoic acid 

structure
  • CAS No:

    1552-94-9

  • Formula:

    C11H10O2

  • Chemical Name:

    5-Phenyl-2,4-pentadienoic acid

  • Synonyms:

    2,4-Pentadienoic acid,5-phenyl-;5-Phenyl-2,4-pentadienoic acid;Cinnamalacetic acid;β-Styrylacrylic acid;Cinnamylideneacetic acid;NSC 109408;NSC 1778;NSC 63972;BL 1255;1-Carboxy-4-phenyl-1,3-butadiene;1-Carobxy-4-phenyl-1,3-butadiene

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Cinnamylideneacetic acid is a photoresponsive compound which is capable of a photoinduced [2+2] cycloaddition[1].


5-phenylpenta-2,4-dienoic acid is a member of styrenes.

5-Phenyl-2,4-pentadienoic acid Basic Attributes

174.2

174.20

216-298-2

50789|1778

DTXSID2061771

2916399090

Characteristics

37.3

2.8

1.1±0.1 g/cm3

165 °C

356.1°C at 760 mmHg

257.6±13.0 °C

1.616

Safety Information

R36/37/38

S26-S36

P264, P270, P301+P312, P330, P501

H302

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 5 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302 (97.44%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

beta-styrylacrylic acid

5-Phenyl-2,4-pentadienoic acid Use and Manufacturing

Methods of Manufacturing

General procedure: The synthesis of the title compounds (Scheme 1) follows a Knoevenangel condensation of the suitable heteroarylaldehyde (0.01 mol) with malonic acid (0.01 mol) dissolved in 1.12 mL of pyridine and piperidine (0.01 mol). The mixture was refluxed until the emission of CO

2,4-Pentadienoic acid, 5-phenyl-: INACTIVE

Computed Properties

Molecular Weight:174.20
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:174.068079557
Monoisotopic Mass:174.068079557
Topological Polar Surface Area:37.3
Heavy Atom Count:13
Complexity:210
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.