Diethylene glycol monoethyl ether

134.17

134.17

1736441

203-919-7

A1A1I8X02B

0039

408451

DTXSID2021941

Colorless liquid

29094400

38.7

-0.5

Clear colorless Liquid

0.989 g/cm³

-76 °C

196 °C

205 °F

1.420

Micible with water.

Store below +30°C.

0.12 mm Hg ( 20 °C)

4.63 (vs air)

Oral-Rat LD50: 5500 mg/kg; Oral-Mouse LD50: 6600 mg/kg

Combustible in case of open flame, high temperature and strong oxidant; burning emits irritating smoke

1.8-12.2%(V)

Mild, pleasant odor

BITTER

5.72e-11 cm3/molecule*sec

Henry's Law constant = 2.23X10-8 atm-cu m/mol at 25 °C (est)

Very hygroscopic|Slightly viscous. Stable. Wt/gal: 8.55 Lb at 20 °C|Blush resistance at 27 °C: 76% rh|Specific heat = 2.31 J/g K

Slightly denser than water and soluble in water. Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick, 1979 p.151-154, 164].

Alcohols and Polyols

Peroxidizable Compound

Mixing diethylene glycol monoethyl ether in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid and oleum, NFPA 1991.

400 °F (USCG, 1999)|400 °F (204 °C)|204 °C

Lower flammable limit: 1.2% by volume; Upper flammable limit: 23.5% AT 360 °F (182 °C) by volume

NONH for all modes of transport

1

36-20-36/37/38

23-24/25-39-26-36

KK8750000

Xn,Xi

Complete packaging, light loading and unloading; warehouse ventilated, away from open flame, high temperature, and stored separately from oxidant

Stable. Combustible. Note wide explosion limits. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.

P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P311, P321, P330, P337+P313, P403+P233, P405, P501

H302

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

...Can react with oxidizing materials.|Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid

Diethylene glycol monoethyl ether is an indirect food additive for use only as a component of adhesives.

European Chemicals Bureau; IUCLID Dataset, 2- (2-ethoxyethoxy) ethanol CAS # 111-90-0) p.53. Available from the Database Query page at: http://ecb.jrc.it/esis/esis.php as of February 20, 2007.|FAO/WHO Joint Expert Committee on Food Additives; WHO Food Additives Series 30 Diethylene Glycol Monoethyl Ether. Available from Database Query page at: http://www.inchem.org/pages/jecfa.html as of February 20, 2007.

This chemical is combustible. (NTP, 1992)|Combustible. Above 96 °C explosive vapour/air mixtures may be formed.

|Danger|H302 (10.96%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P311, P321, P330, P337+P313, P403+P233, P405, and P501|Aggregated GHS information provided by 4816 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Goggles. (USCG, 1999)|Personnel protection: ... Wear appropriate chemical protective gloves, boots and goggles.

Combustible|COMBUSTIBLE WHEN EXPOSED TO HEAT; CAN REACT WITH OXIDIZING MATERIALS.

If material on fire or involved in fire: Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide. Keep run-off water out of sewers and water sources.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|Excessive exposure to inhaled mist or vapor should, in view of its low volatility, be readily controllable by ordinary precautions, but excessive contact with skin should be strictly avoided.|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.

The liquid is moderately irritating to the eye ...

Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.

Separated from strong oxidants. Ventilation along the floor.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is mildly irritating to the eyes.

The substance defats the skin, which may cause dryness or cracking.

NO open flames. Above 96 °C use a closed system and ventilation.

Use ventilation.

Protective gloves.

Wear safety spectacles.

This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Diethylene glycol monoethyl ether is produced, as an intermediate or final product, by process units covered under this subpart.

| 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury.| 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air.| 0 - Materials that in themselves are normally stable, even under fire conditions.

In a national survey, diethylene glycol monoethyl ether was detected in 5 of 21 industrial categories of wastewater effluents(1). Wastewater from the iron and steel industry contained diethylene glycol monoethyl ether at an average concn of 497 mg/L; 52,189 mg/l for printing and publishing; 175 mg/L for amusement and athletic goods; and 40 mg/L for pulp and paper; other categories included publicly owned treatment works(1).

INDOOR AIR: One of 8 sampling periods from March 2, 1987 to Dec 6, 1988 gave a mean concentration of 4.2 ug/cu m(1/19-3/7/88) for diethylene glycol monoethyl ether taken from the second floor of a telephone switching office in Neenah, WI(1). Diethylene glycol monoethyl ether was detected but not quantified in 1 of 44 emission samples from furniture(2).

Diethylene glycol monoethyl ether was found in air freshener but not in cologne, perfume or soap samples that were tested(1).

practically nontoxic

LD50 Rat oral 7500 mg/kg bw|LD50 Rat oral 6500 mg/kg bw|LD50 Rat oral 1920 mg/kg bw|LD50 Rat oral 5.54 g/kg|For more Non-Human Toxicity Values (Complete) data for DIETHYLENE GLYCOL MONOETHYL ETHER (33 total), please visit the HSDB record page.

Diethylene glycol monoethyl ether (DGMEE; >99% pure) was evaluated in the Reproductive Assessment by Continuous Breeding protocol. Task 1 (dose-range finding) was performed using eight male & 8 female Swiss CD-l mice (8 wks of age)/dose group, which were given 0.0, 1.0, 2.0, 3.0, 4.0 & 5.0% DGMEE in their drinking water (deionized/filtered) for 14 days. During the 14-day exposure, one male in the 5.0% DGMEE group exhibited dehydration on days 8-10 & exhibited dehydration & tremors prior to death on day 11. The % weight gain for the sexes combined was significantly reduced in the 4.0% DGMEE group relative to the 0.0, 1.0 & 2.0% DGMEE groups & in the 5.0% DGMEE group relative to the 0.0, 1.0, 2.0 & 3.0% DGMEE groups. Based on the acute toxicity results (Task 1), drinking water levels of 0.0, 0.25, 1.25 & 2.5% DGMEE were selected for the continuous breeding phase of the study (Task 2). Continuous exposure of CD-l mice (11 weeks of age at outset) to up to 2.5% DGMEE had no effect on the number of pairs able to produce at least 1 litter. In addition, DGMEE had no influence on the number of litters/pair, live pups/litter, proportion of pups born alive, or sex (males/total) of pups born alive. In contrast, continuous exposure to the low dose of DGMEE did significantly reduce the adjusted mean live male pup weight & exposure to 2.5% DGMEE significantly reduced the adjusted mean live female pup weight relative to the control group. Due to the minimal effects of DGMEE on fertility & reproductive performance in the Task 2 parental mice (F0 generation), the second generation was evaluated in only the control & high dose groups (Task 4). Each weanling was maintained on the same treatment as their Task 2 parents. Body weights of the F1 male & female offspring continuously exposed to 2.5% DGMEE were slightly depressed at birth, at weaning & at 74 + 10 days of age relative to control F1 male & female offspring. At 74 + 10 days of age, a male & female from different litters within treatment groups were cohabited for 1 wk. The pairs were then separated & the females allowed to deliver their litters. Continuous exposure of the mice to DGMEE had no statistically significant effects on mating behavior, fertility rate, number of live pups/litter, proportion of pups born alive, sex males/total of pups born alive or live pup weight. The 0.0 & 2.5% DGMEE F1 parental mice were necropsied at the conclusion of Task 4. Sperm assessment indicated no significant differences in the sperm concn or % abnormal sperm in the cauda epididymis between male mice exposed to 0.0 or 2.5% DGMEE. Conversely, sperm samples from mice in the 2.5% DGMEE group had significantly fewer motile sperm than did the controls. Although body weight was unaffected, the adjusted liver weight was significantly increased & the adjusted brain weight was significantly decreased in males & females exposed to 2.5% DGMEE relative to controls. Under the conditions of this reproductive study, diethylene glycol monoethyl ether (at doses as high as 2.5% in the drinking water) was not a reproductive toxicant in either F0 or F1 breeding pairs of Swiss CD-l mice, although DGMEE was associated with significantly decreased sperm motility in the F1 males. DGMEE (2.5% in the drinking water) increased liver weight & decreased brain weight in both sexes of the F1 generation.

Diethylene glycol monoethyl ether's production and use as a solvent for nitrocellulose, resins, mineral oils, dyes, soaps, wood stains, textile printing, lacquers, and organic synthesis and as a diluent for brake fluid(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 12(SRC), determined from a log Kow of -0.54(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether is expected to have very high mobility in soil(SRC). Volatilization of diethylene glycol monoethyl ether from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2.2X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 0.126 mm Hg(4), and assigned value for water solubility of 1X10+6 mg/L (miscible)(5). Diethylene glycol monoethyl ether is expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(4). Aerobic screening test data(6-11) indicate that rapid aerobic biodegradation is likely to be the most important mechanism for the removal of diethylene glycol monoethyl ether from soil. Biodegradation of 48%(6) to 87%(7) were reported in non-acclimated cultures incubated for 20 days.|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 12(SRC), determined from a log Kow of -0.54(2) and a regression-derived equation(3), indicates that diethylene glycol monoethyl ether is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2.2X10-8 atm-cu m/mole(SRC), derived from its vapor pressure, 0.126 mm Hg(4), and assigned value for water solubility of 1X10+6 mg/L (5)(miscible). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Diethylene glycol monoethyl ether is not expected to undergo hydrolysis or direct photolysis in aquatic environments(SRC). Alcohols and ethers are generally resistant to hydrolysis(3). They do not absorb UV light in the environmental range of >290 nm and are commonly used as solvents for obtaining UV spectra(14). Aerobic screening test data(8-13) indicate that rapid aerobic biodegradation is likely to be the most important mechanism for the removal of diethylene glycol monoethyl ether from aquatic systems. Biodegradation of 48%(8) to 87%(9) were reported in non-acclimated cultures incubated for 20 days.|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethylene glycol monoethyl ether, which has a vapor pressure of 0.126 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethylene glycol monoethyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 6.7 hours(SRC), calculated from its rate constant of 5.72X10-11 cu cm/molecule-sec at 23 °C(3). Diethylene glycol monoethyl ether does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4).

The rate constant for the vapor-phase reaction of diethylene glycol monoethyl ether with photochemically-produced hydroxyl radicals has been measured as 5.72X10-11 cu cm/molecule-sec at 23 °C(1). This corresponds to an atmospheric half-life of about 6.7 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). Alcohols and ethers are generally resistant to hydrolysis(3). They do not absorb UV light at environmentally significant wavelengths, >290 nm, and are commonly used as solvents for obtaining UV spectra(4). Therefore, diethylene glycol monoethyl ether is not expected to undergo hydrolysis or direct photolysis in the environment.

An estimated BCF of 3 was calculated in fish for diethylene glycol monoethyl ether(SRC), using a log Kow of -0.54(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of diethylene glycol monoethyl ether is estimated as 12(SRC), using a log Kow of -0.54(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that diethylene glycol monoethyl ether is expected to have very high mobility in soil.

The Henry's Law constant for diethylene glycol monoethyl ether is estimated as 2.2X10-8 atm-cu m/mole(SRC) derived from its vapor pressure, 0.126 mm Hg(1), and assigned value for water solubility of 1X10+6 mg/L (miscible)(2). This Henry's Law constant indicates that diethylene glycol monoethyl ether is expected to be essentially nonvolatile from water surfaces(3). The potential for volatilization of diethylene glycol monoethyl ether from dry soil surfaces may exist(SRC) based upon its vapor pressure(1).

DRINKING WATER: Diethylene glycol monoethyl ether was listed as a drinking water contaminant in a survey of US cities including Pomona, Escondido, Lake Tahoe and Orange Co, CA and Dallas, Washington, DC, Cincinnati, Philadelphia, Miami, New Orleans, Ottumwa, IA, and Seattle(1).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 576,490 workers (222,887 of these are female) are potentially exposed to diethylene glycol monoethyl ether in the US(1). Occupational exposure to diethylene glycol monoethyl ether may occur through inhalation and dermal contact with this compound at workplaces where diethylene glycol monoethyl ether is produced or used(SRC). Monitoring and use data indicate that the general population may be exposed to diethylene glycol monoethyl ether via inhalation of ambient air, ingestion of drinking water, and dermal contact with this compound and other consumer products containing diethylene glycol monoethyl ether(SRC).

It has been estimated that the single oral dose /of diethylene glycol/ lethal for humans is approximately 1 ml/kg. /Diethylene glycols/

To assist evaluation of the hazards of skin contact with selected undiluted glycol ethers, their absorption across isolated human abdominal epidermis was measured in vitro. Epidermal membranes were set up in glass diffusion cells and, following an initial determination of permeability to tritiated water, excess undiluted glycol ether was applied to the outer surface for 8 hr. The appearance of glycol ether in an aqueous receptor phase bathing the underside of the epidermis was quantified by a gas chromatographic technique. A final determination of tritiated water permeability was compared with initial values to establish any irreversible alterations in epidermal barrier function induced by contact with the glycol ethers. 2-methoxyethanol (EM) was most readily absorbed (mean steady rate 2.82 mg/sq cm/hr), and a relatively high absorption rate (1.17 mg/sq cm/hr) was also apparent for 1-methoxypropan-2-ol (PM). There was a trend of reducing absorption rate with increasing molecular weight or reducing volatility for monoethylene glycol ethers (EM, 2.82 mg/sq cm/hr; 2-ethoxyethanol, EE, 0.796 mg/sq cm/hr; 2-butoxyethanol, EB, 0.198 mg/sq cm/hr) and also within the diethylene glycol series: 2-(2-methoxyethoxy) ethanol (DM, 0.206 mg/sq cm/hr); 2-(2-ethoxyethoxy) ethanol (DE, 0.125 mg/sq cm/hr) and 2-(2-butoxyethoxy) ethanol (DB, 0.035 mg/sq cm/hr). The rate of absorption of 2-ethoxyethyl acetate (EEAc) was similar to that of the parent alcohol, EE. Absorption rates of diethylene glycol ethers were slower than their corresponding monoethylene glycol equivalents. Combination of intrinsic toxicity and ability to pass across skin contribute to assessment of hazards of contact with undiluted glycol ethers.|When a single /oral/ dose of diethylene glycol monoethyl ether (11.2 mmol) was given to an adult human volunteer (sex and age not specified) about 68% of the dose was excreted in the urine as (2-ethoxyethoxy)acetic acid within 12 hr.|The quantitative urinary excretion of diethylene glycol monoethyl ether was investigated in the rabbit after oral, intravenous, subcutaneous and percutaneous administration. After oral dosing of two animals at a level of 5 mL/kg bw, both animals died during the first day and total excretion was only 0.8% and 0.33%. After intravenous administration to 15 rabbits at dose levels of 0.5-3.4 mL/kg most of the dose was excreted during the first day (for 13/15 rabbits), the percentage excreted tending to increase with dose. After a single parenteral dose of 1.0-3.0 mL/kg, urinary excretion was monitored for up to 4 consecutive days. Excretion was high in the first 24 hr and the total percentage of the dose excreted in urine increased with dose. After repeated daily parenteral doses of 0.16, 0.32 or 0.63 mL/kg bw, total urinary excretion increased with dose and equalled 4.7, 5.0 and 11.6%, respectively.|The oral administration fo 1503 mg Diethylene glycol monoethyl ether to a normal man resulted in the excretion of 1140 mg of 2-ethoxyethoxyacetic acid, 69 % of the total dose, within 12 hr.

...Carbitol is largely destroyed in body or conjugated with glucuronic acid and excreted as the glucuronate. ...This metabolic peculiarity may explain its lesser toxicity when compared with that of diethyl, methyl and butyl cellosolve.

None expected. (USCG, 1999)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

/HUMAN EXPOSURE STUDIES/ ... Human volunteers showed neither irritation nor signs of sensitization when the material was tested at a 20 percent level in petroleum for a 48 hour closed patch test.|/HUMAN EXPOSURE STUDIES/ Patch tests were conducted on commercial grade diethylene glycol monoethyl ether in 98 subjects using an initial contact period of 7 days, followed by 10 days withdrawal then a further 3 day test period. Definite reactions were reported in 7/98 persons but a standardized scoring method was not used.|/HUMAN EXPOSURE STUDIES/ Patch tests were conducted on undiluted commercial grade diethylene glycol monoethyl ether (containing 30% ethylene glycol) in 99 subjects using 48 hr exposure with subsequent examination at intervals up to 1 month. Slight positive reactions (faint erythema persisting for 48 hr after removal) occurred in 24/99 subjects. Similar tests on aqueous dilutions of pure diethylene glycol monoethyl ether (0.2% ethylene glycol) or carbitol solvent were carried out on 31 subjects. No reactions were seen with 5% solutions of either material and a concentration-related increasing frequency of reactions (faint erythema) was seen at higher concentrations. Undiluted materials led to 14 reactions with the carbitol solvent and 5 reactions with the pure material|/HUMAN EXPOSURE STUDIES/ Commercial grade diethylene glycol monoethyl ether was rubbed on the inner wrist surface for 5 mins daily on 10 consecutive days. Irritant effects were noted with 3/60 subjects showing congestion or papules, mainly originating at hair follicles and persisting for several hours|For more Human Toxicity Excerpts (Complete) data for DIETHYLENE GLYCOL MONOETHYL ETHER (12 total), please visit the HSDB record page.

carbitol

Dry skin.

Redness.

23% CONSUMED AS A DILUENT FOR HYDRAULIC BRAKE FLUIDS; 77% CONSUMED IN OTHER APPLICATIONS INCLUDING USE AS A SOLVENT IN PROTECTIVE COATINGS, TEXTILE PRINTING & DYEING, AND IN COSMETICS & TOILETRIES (1972)

Grade: Technical

All other basic organic chemical manufacturing|Ethanol, 2-(2-ethoxyethoxy)-: ACTIVE|Temperature, pressure, mole ratios of reactants and catalysts are chosen to yield the desired product mix. High ratios of ethylene oxide to alcohol are used to favor production of monoethers of diethylene glycol.

Method: OSHA PV2013; Procedure: gas chromatography with flame ionization detector; Analyte: diethylene glycol ethyl ether; Matrix: air; Detection Limit: 0.09 ppm.|Gas chromatography is likely to be the analytical method for final analysis. Infrared absorption is sometimes used. /Glycol ethers/|Analyte: diethylene glycol monoethyl ether; matrix: chemical identification; procedure: infrared absorption spectrophotometry with comparison to standards|Analyte: diethylene glycol monoethyl ether; matrix: chemical identification; procedure: retention time of the major peak of the liquid chromatogram with comparison to standards|Analyte: diethylene glycol monoethyl ether; matrix: chemical purity; procedure: gas chromatography with flame-ionization detection

Food Additives -> CARRIER_SOLVENT; -> JECFA Functional Classes|Cosmetics -> Humectant; Solvent

Food Additives -> CARRIER_SOLVENT;