Acetic acid, 2-(aminothioxomethyl)hydrazide

white to slightly beige crystalline powder

Intermediate 26: 2-Acetylhvdrazinecarbothioamide; To a solution of thiosemicarbazide (9.1 Og, O.I Omol) in anhydrous THF (100ml) was added acetyl chloride (8.64g, 0.11 mol) at OA suspension of thiosemicarbazide 2 (5.0 g, 55 mmol) in glacial acetic acid (25 ml) was heated under reflux for 2 h to give a clear solution. The crude acetylthiosemicarbazide slowly crystallised from solution on cooling. It was recrystallised from ethanol to give the pure product. Yield (4.4 g, 60percent), m.p. 163-165 °C (lit.A suspension of thiosemicarbazide 2 (5.0 g, 55 mmol) in glacial acetic acid (25 ml) was heated under reflux for 2 h to give a clear solution. The crude acetylthiosemicarbazide slowly crystallised from solution on cooling. It was recrystallised from ethanol to give the pure product. Yield (4.4 g, 60%), m.p. 163-165 C (lit.1 m.p. 166 C).

Molecular Weight:133.18
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Exact Mass:133.03098303
Monoisotopic Mass:133.03098303
Topological Polar Surface Area:99.2
Heavy Atom Count:8
Complexity:113
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes