Glycol dibutyl ether

174.28

174.28

203-976-8

1HZO49D869

1149

DTXSID5074268

Almost colorless liquid

2909199090

18.5

2.5

Ethylene glycol dibutyl ether is a colorless liquid. (USCG, 1999)

0.837 g/cm³ @ Temp: 25 °C

-69 °C

203.6 °C @ Press: 760 Torr

85°C

1.416

Solubility in water: poor

9.0X10-2 mm Hg at 20 deg C

Relative vapour density (air = 1): 6

Oral-Rat  LD50: 3250  mg/kg

Combustible in case of fire, high temperature and strong oxidants; burning produces irritating smoke

Slight odor

Henry's Law constant = 1.03X10-5 atm-cu m/mol at 25 °C (est)

Hydroxyl radical reaction rate constant = 2.78X10-11 cu cm/molec-sec at 25 °C (est)

Oxidizes in air to form unstable peroxides that may explode spontaneously [Bretherick, 1979 p.151-154, 164].

Ethers

Peroxidizable Compound

ETHYLENE GLYCOL DIBUTYL ETHER may react violently with strong oxidizing agents. May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents. May initiate the polymerization of isocyanates and epoxides. Relatively inert in other reactions, which typically involve the breaking of the carbon-oxygen bond.

23-24/25

KH9450000

Warehouse ventilated, low temperature and dry

P264, P280, P305+P351+P338, P33, P313

H319

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid

Special Hazards of Combustion Products: On decomposition, it emits acrid smoke and irritating fumes. (USCG, 1999)|Combustible. Above 85 °C explosive vapour/air mixtures may be formed.

|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory.

Fire Extinguishing Agents Not to Be Used: Water may be ineffective. Fire Extinguishing Agents: Dry chemical, alcohol foam, carbon dioxide. (USCG, 1999)|Use water spray, powder, alcohol-resistant foam, carbon dioxide.

Protective goggles or face shield; rubber gloves. (USCG, 1999)

Combustible

Collect leaking liquid in sealable containers. Wash away remainder with plenty of water.

Separated from strong oxidants. Ventilation along the floor.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is mildly irritating to the eyes and skin.

The substance defats the skin, which may cause dryness or cracking.

NO open flames. Above 85 °C use a closed system and ventilation.

Use ventilation.

Protective gloves.

Wear safety spectacles.

| 1 - Materials that, under emergency conditions, can cause significant irritation.| 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air.| 0 - Materials that in themselves are normally stable, even under fire conditions.

moderately toxic

LD50 Rat oral 3250 mg/kg|LD50 Rabbit dermal 3560 mg/kg

Ethylene glycol dibutyl ether's production and use as a solvent(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 17(SRC), determined from a structure estimation method(2), indicates that ethylene glycol dibutyl ether is expected to have very high mobility in soil(SRC). Volatilization of ethylene glycol dibutyl ether from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1X10-5 atm-cu m/mole(SRC), based upon its vapor pressure, 0.09 mm Hg(3), and water solubility, 2000 mg/L(4). Ethylene glycol dibutyl ether is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Biodegradation data were not available(SRC, 2007).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 17(SRC), determined from a structure estimation method(2), indicates that ethylene glycol dibutyl ether is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.09 mm Hg(4), and water solubility, 2000 mg/L(5). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4.9 and 39 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 16(SRC), from its log Kow of 2.48(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation data were not available(SRC, 2007).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethylene glycol dibutyl ether, which has a vapor pressure of 0.09 mm Hg at 20 °C(2), will exist solely in vapor phase in the ambient atmosphere. Vapor-phase ethylene glycol dibutyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 10 hours(SRC), calculated from its rate constant of 3.9X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).

The rate constant for the vapor-phase reaction of ethylene glycol dibutyl ether with photochemically-produced hydroxyl radicals has been estimated as 3.9X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 10 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Ethylene glycol dibutyl ether is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2).

An estimated BCF of 16 was calculated in fish for ethylene glycol dibutyl ether(SRC), using a log Kow of 2.48(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of ethylene glycol dibutyl ether can be estimated to be 17(SRC). According to a classification scheme(2), this estimated Koc value suggests that ethylene glycol dibutyl ether is expected to have very high mobility in soil(SRC).

The Henry's Law constant for ethylene glycol dibutyl ether is estimated as 1X10-5 atm-cu m/mole(SRC) derived from its vapor pressure, 0.09 mm Hg(1), and water solubility, 2000 mg/L(2). This Henry's Law constant indicates that ethylene glycol dibutyl ether is expected to volatilize from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 4.9 days(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 39 days(SRC). Ethylene glycol dibutyl ether's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Ethylene glycol dibutyl ether is not expected to

Occupational exposure to ethylene glycol dibutyl ether may occur through inhalation and dermal contact with this compound at workplaces where ethylene glycol dibutyl ether is produced or used. (SRC)

Moderately toxic by ingestion and skin contact. Irritates skin and eyes. (USCG, 1999)

INHALATION: Call for medical aid. Remove from exposure EYES: Flush with water for at least 15 minutes. SKIN: Wash with copious amounts of water. (USCG, 1999)

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Dry skin. Redness.

Redness.