(±)-Thyroxine
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(±)-Thyroxine
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CAS No:
300-30-1
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Formula:
C15H11I4NO4
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Chemical Name:
(±)-Thyroxine
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Synonyms:
Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-;Thyroxine,DL-;DL-Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-;O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;DL-Thyroxine;(±)-Thyroxine;O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-DL-tyrosine;2-Azaniumyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
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CAS No:
Description
ChEBI: An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Thyroxine is an iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions. It has a role as a mitogen. It is an iodothyronine, a 2-halophenol, an iodophenol, a tyrosine derivative and a non-proteinogenic alpha-amino acid. It is a tautomer of a thyroxine zwitterion.
Characteristics
92.8
4.12 (est)
2.6±0.1 g/cm3
211 °C (decomp)
576.3±50.0 °C at 760 mmHg
302.3±30.1 °C
1.795
Insoluble in ethanol, benzene
Keep container tightly closed in a dry and well-ventilated place.
2.05X10-16 mm Hg at 25 deg C (est)
Safety Information
Extemporaneously prepared liquid dosage forms are needed to administer required medications in infants and young children. The goal of this study was to evaluate the stability of levothyroxine in extemporaneously prepared suspensions stored in plastic prescription bottles under refrigeration and room temperature. Levothyroxine (25 ug/mL) /was/ prepared in two groups of suspensions. /The/ suspensions were stored in plastic prescription bottles under refrigeration and at room temperature. Levot
Computed Properties
Molecular Weight:776.87
XLogP3:2.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:776.6867
Monoisotopic Mass:776.6867
Topological Polar Surface Area:92.8
Heavy Atom Count:24
Complexity:420
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes