Catalpol
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Catalpol
structure -
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CAS No:
2415-24-9
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Formula:
C15H22O10
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Chemical Name:
Catalpol
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Synonyms:
β-D-Glucopyranoside,(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl;Catalpol;β-D-Glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-;(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside;Catalpinoside;De(p-hydroxybenzoyl)catalposide;Catapol;Aucubin 7,8-epoxide;7,8-Epoxyaucubin;27892-32-6;29856-95-9;849811-72-9
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CAS No:
Description
Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.IC50 Value:Target: neuroprotective, anti-inflammatory, and anti-hepatitis virus natural product.In vitro: Catalpol could be encapsulated into composite nanofibers and induce differentiation of hASCs into neural-like cells, which might offer new avenues in nerve regeneration [1].In vivo: The pharmacokinetics of catalpol in normal and doxorubicin-induced chronic kidney disease rats afte
Catalpol is an organic molecular entity. It has a role as a metabolite.
Characteristics
162
-3.59030
powder
1.7±0.1 g/cm3
207 °C
675.6°C at 760 mmHg
362.4±31.5 °C
1.679
-20°C
3.77E-21mmHg at 25°C
Safety Information
NONH for all modes of transport
3
36/37/38
26-36
LZ5776816
Xi
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Catalpol Use and Manufacturing
The main function is to stimulate the production of adrenal cortex hormones, thereby increasing the production of hormones. Catalpol also has anti-inflammatory activity and has been shown to increase the production of androgens produced by the adrenal glands, which leads to increased muscle mass.
Lipids -> Prenol Lipids [PR] -> Isoprenoids [PR01] -> C10 isoprenoids (monoterpenes) [PR0102]
Computed Properties
Molecular Weight:362.33
XLogP3:-3.2
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:362.12129689
Monoisotopic Mass:362.12129689
Topological Polar Surface Area:162
Heavy Atom Count:25
Complexity:542
Defined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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