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Catalpol

Catalpol structure

Catalpol 

structure
  • CAS No:

    2415-24-9

  • Formula:

    C15H22O10

  • Chemical Name:

    Catalpol

  • Synonyms:

    β-D-Glucopyranoside,(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl;Catalpol;β-D-Glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-;(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside;Catalpinoside;De(p-hydroxybenzoyl)catalposide;Catapol;Aucubin 7,8-epoxide;7,8-Epoxyaucubin;27892-32-6;29856-95-9;849811-72-9

  • Categories:

    Natural Products  >  Iridoid Derivatives

Description

Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.IC50 Value:Target: neuroprotective, anti-inflammatory, and anti-hepatitis virus natural product.In vitro: Catalpol could be encapsulated into composite nanofibers and induce differentiation of hASCs into neural-like cells, which might offer new avenues in nerve regeneration [1].In vivo: The pharmacokinetics of catalpol in normal and doxorubicin-induced chronic kidney disease rats afte


Catalpol is an organic molecular entity. It has a role as a metabolite.

Catalpol Basic Attributes

362.33

362.33

219-324-0

DTXSID60178850

29389090

Characteristics

162

-3.59030

powder

1.7±0.1 g/cm3

207 °C

675.6°C at 760 mmHg

362.4±31.5 °C

1.679

-20°C

3.77E-21mmHg at 25°C

Safety Information

NONH for all modes of transport

3

36/37/38

26-36

LZ5776816

Xi

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

catalpol

Catalpol Use and Manufacturing

Uses

The main function is to stimulate the production of adrenal cortex hormones, thereby increasing the production of hormones. Catalpol also has anti-inflammatory activity and has been shown to increase the production of androgens produced by the adrenal glands, which leads to increased muscle mass.

Lipids -> Prenol Lipids [PR] -> Isoprenoids [PR01] -> C10 isoprenoids (monoterpenes) [PR0102]

Computed Properties

Molecular Weight:362.33
XLogP3:-3.2
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:362.12129689
Monoisotopic Mass:362.12129689
Topological Polar Surface Area:162
Heavy Atom Count:25
Complexity:542
Defined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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