3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE
-
3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE
structure -
-
CAS No:
2538-50-3
-
Formula:
C10H14ClNO
-
Chemical Name:
3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE
-
Synonyms:
3-Methylaminopropiophenone;3-(METHYLAMINO)PROPIOPHENONEHCL;3-Methylamino-1-Phenyl-1-AcetoneHCl;3-Methylaminophenylpropanonehydrochloride;3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE;N,N-dibutylbenzene-1,4-diaMinehydrochloride;3-Methylamino-1-phenylpropan-1-onehydrochloride;1-(MethylaMino)-3-phenylpropan-2-onehydrochloride;3-(Methylamino)-1-phenyl-1-propanonehydrochloride;3-Methylaminophenylpropanonehydrochloride-(Methylamino)-1-phenyl-1-propanonehydrochloride
- Categories:
-
CAS No:
Characteristics
29.1
2.67170
1.002g/cm3
139-141 °C(Solv: acetone (67-64-1))
274.7ºC at 760 mmHg
114.1ºC
1.515
0.00534mmHg at 25°C
3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE Use and Manufacturing
Acetophenone (25mmol), Methylamine hydrochloride (27.5mmol), Formaldehyde (35mmol), Concentrated hydrochloric acid (0.125 mmol) was added ethanol (12.5mL), and110 sealed vessel was heated 20h.After cooling to room temperature, the solvent was removed by distillation under reduced pressure was added ethyl acetate (25mL). Stirring was continued for 4h, filtered to give the crude product residue was washed with ethyl acetate, recrystallized from isopropanol to give the product 2a. Yield: 60-70percent.Flame dried (flame dried) 100 of the sealed tube (sealed tube) in acetophenone (3.1g, 25 mmol), paraformaldehyde (1.05 g, 35 mmol) and N-methylamine hydrochloride(N-methyl amine hydrochloride , 1.86 g, put 27.5 mmol) was dissolved in 12.5 absolute ethanol (anhydrous EtOH). The stirred concentrated hydrochloric acid (conc areaction mixture. HCl, was added to 0.125 ) and align the container screw (screwvessel) tightly and heated for 20 hours at 110 ° C. The solvent was evaporated underreduced pressure The reaction mixture was cooled to room temperature. Crude residue(crude residue) was dissolved in ethyl acetate and 50 was vigorously stirred to causeprecipitation. After filtering the precipitate, the crude precipitate (crude precipitate, 4.33g, 87percent) was recrystallized three times in hot IPA.Bright yellow solid (1.98 g, 39.8percent, purity 95percent
Computed Properties
Molecular Weight:199.68
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:199.0763918
Monoisotopic Mass:199.0763918
Topological Polar Surface Area:29.1
Heavy Atom Count:13
Complexity:139
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Recommended Suppliers of 3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE
-
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive -
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 2538-50-3Grade: Industrial GradeContent: 95%
Learn More Other Chemicals
-
11-Chloro-2,3-dihydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
1012884-46-6
-
Trans-(+/-)-11-Chloro-2,3,3a,12b-tetrahydro-2-meth
129385-59-7
-
Triptophenolide methyl ether
74311-48-1
-
2-Butene-1,4-diol Formula
110-64-5
-
6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one Formula
74285-86-2
-
3-Bromoanisole Formula
2398-37-0
-
L-Proline, methyl ester, hydrochloride (1:1) Structure
2133-40-6
-
1-Fluoronaphthalene Structure
321-38-0
-
What is ABT-418 HYDROCHLORIDE
147388-83-8
-
What is Diethyl acetamidomalonate
1068-90-2
3-METHYLAMINO-1-PHENYLACETONEHYDROCHLORIDE
SDSRequest for Quotation