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D,L Carbidopa

D,L Carbidopa structure

CAS No:
302-53-4
Formula:
C10H14N2O4
Chemical Name:
D,L Carbidopa
Synonyms:
a-Hydrazino-a-methyldopa;DL-a-Hydrazino-3,4-dihydroxy-a-methylhydrocinnamic Acid;a-Hydrazino-3,4-dihydroxy-a-methyl-benzenepropanoic Acid;dl-MK 485;NSC 92521;Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-;DL-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid;DL-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid
Categories:
Organic Chemistry > Amides

Description

3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid is a monocarboxylic acid and a member of benzenes.|An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.

Off-White to Grey Powder

ChEBI: 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid is a monocarboxylic acid and a member of benzenes.

D,L Carbidopa Basic Attributes

Molecular Weight：

226.23

Exact Mass：

226.23

NSC Number：

758190|92521

Color/Form：

Pale Yellow to Grey

HScode：

29280000

Characteristics

Density：

1.420±0.06 g/cm3(Predicted)

Melting Point：

203-206°C

Boiling Point：

528.7±50.0 °C(Predicted)

PKA：

3.40±0.14(Predicted)

Critical Temperature & Pressure：

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Drug Information

MeSH：

Compounds and drugs that block or inhibit the enzymatic action of AROMATIC AMINO ACID DECARBOXYLASES. Pharmaceutical agents in this category are used in conjunction with LEVODOPA in order to slow its metabolism. (See all compounds classified as Aromatic Amino Acid Decarboxylase Inhibitors.)|Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. (See all compounds classified as Dopamine Agents.)|Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

MeSH Entry Terms：

Carbidopa

D,L Carbidopa Use and Manufacturing

An inhibitor of aromatic amino acid decarboxylase.