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Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone

Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone structure

CAS No:
2675-35-6
Formula:
C19H14N4O6
Chemical Name:
Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone
Synonyms:
Methanone,bis(4-hydroxyphenyl)-,2-(2,4-dinitrophenyl)hydrazone;Benzophenone,4,4′-dihydroxy-,(2,4-dinitrophenyl)hydrazone;Methanone,bis(4-hydroxyphenyl)-,(2,4-dinitrophenyl)hydrazone;Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone;4,4′-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone;A 007;Bis(4-hydroxyphenyl)methanone (2,4-dinitrophenyl)hydrazone;Sivifene

Description

Sivifene is the phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia (CIN).

Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone Basic Attributes

Molecular Weight：

394.343

Exact Mass：

394.34

UNII：

XAV05295I5

NCI Thesaurus Code：

C61305

HScode：

2928000090

Characteristics

PSA：

153

XLogP3：

4.89810

Density：

1.47

Toxicity：

LD50 oral in rat: 4300mg/kg

Drug Information

Drug Indication：

Investigated for use/treatment in cervical dysplasia/cancer, genital warts, and skin cancer.

MeSH Entry Terms：

4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone

Computed Properties

Molecular Weight:394.3
XLogP3:5.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:394.09133418
Monoisotopic Mass:394.09133418
Topological Polar Surface Area:157
Heavy Atom Count:29
Complexity:579
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone

Description
Basic Attributes
Characteristics
Drug Information
Computed Properties
Learn More Other Chemicals

Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone

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