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Home > Encyclopedia > Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1)

Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1)

Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1) structure

Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1) 

structure
  • CAS No:

    302-83-0

  • Formula:

    C10H16NO.Br

  • Chemical Name:

    Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1)

  • Synonyms:

    Benzenaminium,N-ethyl-3-hydroxy-N,N-dimethyl-,bromide (1:1);Ammonium,ethyl(m-hydroxyphenyl)dimethyl-,bromide;Benzenaminium,N-ethyl-3-hydroxy-N,N-dimethyl-,bromide;Ethyl(m-hydroxyphenyl)dimethylammonium bromide;Edrophonium bromide;Oedrophanium bromide;Tensilon bromide

  • Categories:

    Organic Chemistry  >  Amides

Description

A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.

Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, bromide (1:1) Basic Attributes

246.148

245.04200

KX008093VW

2923900090

Characteristics

20.2

3.37530

LD50 oral in mouse: 600mg/kg

Drug Information

Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)|Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. (See all compounds classified as Cholinesterase Inhibitors.)

Bromide, Edrophonium

Computed Properties

Molecular Weight:246.14
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:245.04153
Monoisotopic Mass:245.04153
Topological Polar Surface Area:20.2
Heavy Atom Count:13
Complexity:145
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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