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Hydroxydione

Hydroxydione structure

Hydroxydione 

structure
  • CAS No:

    303-01-5

  • Formula:

    C21H32O3

  • Chemical Name:

    Hydroxydione

  • Synonyms:

    Pregnane-3,20-dione,21-hydroxy-,(5β)-;5β-Pregnane-3,20-dione,21-hydroxy-;(5β)-21-Hydroxypregnane-3,20-dione;Hydroxydione;5β-Pregnan-21-ol-3,20-dione;5β-Pregnane-21-ol-3,20-dione;21-Hydroxy-5β-pregnane-3,20-dione;5β-Dihydrodeoxycorticosterone;NSC 86000;360-69-0

Description

ChEBI: A 3-oxo steroid with 5beta-configuration formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond.


5beta-dihydrodeoxycorticosterone is a 3-oxo-5beta-steroid formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond. It has a role as a human xenobiotic metabolite. It is a 21-hydroxy steroid, a 20-oxo steroid, a 3-oxo-5beta-steroid and a primary alpha-hydroxy ketone. It derives from an 11-deoxycorticosterone. It derives from a hydride of a 5beta-pregnane.|Hydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.

Hydroxydione Basic Attributes

332.484

332.48

B7VFN88375

86000

Characteristics

54.4

3.43

1.11g/cm3

195-197 °C

468.6ºC at 760 mmHg

251.3ºC

1.531

1.56e-02 g/l

Drug Information

Endogenous compounds or drugs that affect neuronal excitability through modulation of specific ionotropic receptors (e.g., GABA-A RECEPTORS). Endogenous neurosteroids are steroid hormones de novo synthesized by neurons and glial cells from steroid metabolite precursors (e.g., PREGNENOLONE). (See all compounds classified as Neurosteroids.)

21-hydroxy-5 alpha-pregnane-3,20-dione

Computed Properties

Molecular Weight:332.5
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:332.23514488
Monoisotopic Mass:332.23514488
Topological Polar Surface Area:54.4
Heavy Atom Count:24
Complexity:555
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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