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Allocholic acid

Allocholic acid structure

Allocholic acid 

structure
  • CAS No:

    2464-18-8

  • Formula:

    C24H40O5

  • Chemical Name:

    Allocholic acid

  • Synonyms:

    Cholan-24-oic acid,3,7,12-trihydroxy-,(3α,5α,7α,12α)-;5α-Cholan-24-oic acid,3α,7α,12α-trihydroxy-;5α-Cholanic acid,3α,7α,12α-trihydroxy-;(3α,5α,7α,12α)-3,7,12-Trihydroxycholan-24-oic acid;Allocholic acid;3α,7α,12α-Trihydroxy-5α-cholanoic acid;5α-Cholic acid;5α-Allocholic acid;NPLC 0115;2148334-98-7

Description

Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. Allocholic acid is also a potent and specific stimulant of the adult olfactory system[1][2][3].


Solid


Allocholic acid is an allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. It has a role as a marine metabolite, a rat metabolite and a human metabolite. It is a C24-steroid, a 3alpha-hydroxy steroid, a 7alpha-hydroxy steroid, a 12alpha-hydroxy steroid and an allo-bile acid. It is a conjugate acid of an allocholate.

Allocholic acid Basic Attributes

408.57

408.57

Characteristics

97.99000

3.44870

Solid

1.184g/cm3

238-240 °C

583.9ºC at 760 mmHg

321ºC

1.558

-20°C Freezer

Drug Information

allocholic acid

Allocholic acid Use and Manufacturing

Uses

Has wide-spread occurrence in a number of sources, including man as a major biliary metabolite

Lipids -> Sterol Lipids [ST] -> Bile acids and derivatives [ST04] -> C24 bile acids, alcohols, and derivatives [ST0401]

Computed Properties

Molecular Weight:408.6
XLogP3:3.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:408.28757437
Monoisotopic Mass:408.28757437
Topological Polar Surface Area:98
Heavy Atom Count:29
Complexity:637
Defined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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